Nervous system

Eyal Bar-Kochba, Catherine M. Carneal, Vanessa D. Alphonse, et al. Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures. Frontiers in Bioengineering and Biotechnology. 2025;13. doi:10.3389/fbioe.2025.1553609

Snehal Raut, Aditya Bhalerao, Luca Cucullo. A Guided Approach to Establish a Functional Humanized Brain-on-a-Chip Microfluidic Model of the Neurovascular System. In: Evangelia Papadimitriou, Constantinos M. Mikelis, eds. Methods in Cardiovascular and Lymphatic Biology. New York, NY: Springer US; 2025:35-52. https://doi.org/10.1007/978-1-0716-4706-6_4.

R. Chris Estridge, Z. Begum Yagci, Dilara Sen, et al. Loss of UBE3A impacts both neuronal and non-neuronal cells in human cerebral organoids. Communications Biology. 2025;8(1):838. doi:10.1038/s42003-025-08262-x

Camiel C. A. Mannens, Lijuan Hu, Peter Lönnerberg, et al. Chromatin accessibility during human first-trimester neurodevelopment. Nature. 2025;647(8088):179-186. doi:10.1038/s41586-024-07234-1

Li Wang, Cheng Wang, Juan A. Moriano, et al. Molecular and cellular dynamics of the developing human neocortex. Nature. 2025;647(8088):169-178. doi:10.1038/s41586-024-08351-7

Matthew G. Keefe, Marilyn R. Steyert, Tomasz J. Nowakowski. Lineage-resolved atlas of the developing human cortex. Nature. 2025;647(8088):194-202. doi:10.1038/s41586-025-09033-8

Adrià Casamitjana, Matteo Mancini, Eleanor Robinson, et al. A probabilistic histological atlas of the human brain for MRI segmentation. Nature. 2025:1-8. doi:10.1038/s41586-025-09708-2

James G. Shamul, Zhiyuan Wang, Hyeyeon Gong, et al. Meta-analysis of the make-up and properties of in vitro models of the healthy and diseased blood–brain barrier. Nature Biomedical Engineering. 2025;9(4):566-598. doi:10.1038/s41551-024-01250-2

Alice E. Stanton, Adele Bubnys, Emre Agbas, et al. Engineered 3D immuno-glial-neurovascular human miBrain model. Proceedings of the National Academy of Sciences. 2025;122(42):e2511596122. doi:10.1073/pnas.2511596122

Kai Cheng, Autumn Williams, Anannya Kshirsagar, et al. Machine learning-enabled detection of electrophysiological signatures in iPSC-derived models of schizophrenia and bipolar disorder. APL Bioengineering. 2025;9(3):036118. doi:10.1063/5.0250559