Cardiovascular system

Diana M. Rojas-González, Frederic Wolf, Nicole Schaaps, et al. Evaluation of tissue-engineered blood vessels as three-dimensional in vitro testing system in cardiovascular research. Frontiers in Bioengineering and Biotechnology. 2026;14. doi:10.3389/fbioe.2026.1729469

Sina Kheiri, Jessica Shah, Peiyuan Chai, et al. 4D force patterning enables spatial control of angiogenesis. Proceedings of the National Academy of Sciences. 2026;123(28):e2532667123. doi:10.1073/pnas.2532667123

Ramak Khosravi, Milica Radisic. Heart-on-a-chip and vasculature-on-a-chip platforms as models of cardiovascular disease. Nature Reviews Cardiology. 2026:1-18. doi:10.1038/s41569-026-01255-1

Runxin Wu, Guinevere Ferreira, Nusrat Sadia Khan, et al. Digital twins and digital models of the human circulatory system. Nature Reviews Bioengineering. 2026;4(7):594-613. doi:10.1038/s44222-026-00427-5

Young Hyun Kim, Young Hoon Son, Yuri Choi, Min Suk Kim, Sung-Jin Park, Keel Yong Lee. Advanced in vitro cardiac models for drug evaluation: integration of organoids, engineered tissues, and microphysiological systems. Microsystems & Nanoengineering. 2026;12(1):162. doi:10.1038/s41378-026-01249-6

Beiqin Liu, Shuyue Wang, Hong Ma, et al. Heart-on-a-chip: a revolutionary organ-on-chip platform for cardiovascular disease modeling. Journal of Translational Medicine. 2025;23(1):132. doi:10.1186/s12967-024-05986-y

Chengyi Tu, Arianne Caudal, Yu Liu, Sanjiv M. Narayan, Joseph C. Wu. Modeling heart rhythm using human engineered heart tissues. Nature Protocols. 2025:1-24. doi:10.1038/s41596-025-01217-w

Ana Kojic, Javid Moslehi, Bonnie Ky, Joseph C. Wu. Cardiometabolic disease and cardio-oncology: Insights from iPSC models and tissue engineering. Cell Reports Medicine. 2025;6(9):102261. doi:10.1016/j.xcrm.2025.102261

Cristiane M. Franca, Maria Elisa Lima Verde, Alice Corrêa Silva-Sousa, et al. Perivascular cells function as key mediators of mechanical and structural changes in vascular capillaries. Science Advances. 2025;11(2):eadp3789. doi:10.1126/sciadv.adp3789

M. Iveth Garcia, Keri Dame, Verena Charwat, et al. Human induced pluripotent stem cell-derived cardiomyocytes and their use in a cardiac organ-on-a-chip to assay electrophysiology, calcium and contractility. Nature Protocols. 2025:1-47. doi:10.1038/s41596-025-01166-4