Bioengineering and model development

Satoru Fujii, Scott T. Espenschied, Vibha Anand, et al. Quantifying the fidelity of in vitro human cell culture systems using a biomedical foundation model. Proceedings of the National Academy of Sciences. 2026;123(12):e2520482123. doi:10.1073/pnas.2520482123

Navya Mishra, Rajaram Kaveti, Pei Liu, et al. Carbon nanotube microelectrode arrays enable scalable and accessible electrophysiological recordings of cerebral organoids. npj Biosensing. 2026;3(1):20. doi:10.1038/s44328-026-00088-9

Barbara Pavan, Giada Botti, Alessandro Dalpiaz, Raffaello Sbordoni, Abdullah Talari, Valon Llabjani. A new microphysiological platform to study the permeation of neuroactive agents across intestinal and brain barriers. Biofabrication. 2026;18(2):025013. doi:10.1088/1758-5090/ae514c

Duy Bao Tran Nguyen, Ahmed S. M. Ali, Dongwei Wu, et al. Functional siRNA Delivery via Jet Nebulization: Proof-of-Concept IL-1ß Silencing in Macrophage-like THP-1 Cells. International Journal of Molecular Sciences. 2026;27(6). doi:10.3390/ijms27062915

Jungwook Paek, Lakshminarayan Reddy Teegala, Farid Alisafaei, et al. Mechanical force-induced tissue remodelling in a clinically relevant microphysiological model of asthmatic human lungs. Nature Biomedical Engineering. 2026:1-22. doi:10.1038/s41551-026-01669-9

Joel P. Joseph, Sriram Bharath Gugulothu, Dipankar Nandi, Kaushik Chatterjee. Next-generation immune models: bioinks, 3D bioprinting, and future directions. Trends in Biotechnology. 2026. doi:10.1016/j.tibtech.2026.04.017

Alastair G. Stewart, Avanka Gunatilaka, Bryan Gao. Should culture media for microphysiological systems be nutritionally physiological? Nature Reviews Bioengineering. 2025;3(5):357-358. doi:10.1038/s44222-025-00290-w

Kari-Pekka Skarp, Bahar Yetkin-Arik, Suze A. Jansen, Caroline A. Lindemans, Magdalena J. Lorenowicz. Protocol for modeling the repair of intestinal damage by co-culturing mesenchymal stromal/stem cells and intestinal organoids. STAR protocols. 2025;7(1):104292. doi:10.1016/j.xpro.2025.104292

Alexandra N. Borelli, Kristyn S. Masters. Developing sex-accurate cell culture environments. Nature Reviews Bioengineering. 2025;3(1):2-3. doi:10.1038/s44222-024-00265-3

Chao-Fan He, Tian-Hong Qiao, Guang-Hao Wang, Yuan Sun, Yong He. High-resolution projection-based 3D bioprinting. Nature Reviews Bioengineering. 2025;3(2):143-158. doi:10.1038/s44222-024-00218-w