Translation and validation

Vaishali Sahasrabudhe, Timothy Nicholas, Gianluca Nucci, Cynthia J Musante, Brian Corrigan. Impact of Model-Informed Drug Development on Drug Development Cycle Times and Clinical Trial Cost. Clinical Pharmacology & Therapeutics. 2025;118(2):378-385. doi:10.1002/cpt.3636

Alexis R. Katz, Margaret P. Huntwork, Jay K. Kolls, et al. Impact of psychological stressors on natural killer cell function: A comprehensive analysis based on stressor type, duration, intensity, and species. Physiology & Behavior. 2025;288:114734. doi:10.1016/j.physbeh.2024.114734

Hamideh Frühwein, Norbert W. Paul. “Lost in translation?” Animal research in the era of precision medicine. Journal of Translational Medicine. 2025;23(1):152. doi:10.1186/s12967-025-06084-3

Sarah E. Wolfensohn, Vera Baumans, F. Josef van der Staay, Saskia S. Arndt. Implications of stress for animal welfare and animal-based research†. Laboratory Animals. 2025:00236772251396310. doi:10.1177/00236772251396310

Alberto Granzotto, Bryce Vissel, Stefano L Sensi. Lost in translation: Inconvenient truths on the utility of mouse models in Alzheimer’s disease research. Timothy E Behrens, ed. eLife. 2024;13:e90633. doi:10.7554/eLife.90633

Ivana Jaric, Bernhard Voelkl, Irmgard Amrein, et al. Using mice from different breeding sites fails to improve replicability of results from single-laboratory studies. Lab Animal. 2024;53:18-22. doi:10.1038/s41684-023-01307-w

Ingrid Berg, Pia Härvelid, Wolfgang Emanuel Zürrer, Marianna Rosso, Daniel S. Reich, Benjamin Victor Ineichen. Which experimental factors govern successful animal-to-human translation in multiple sclerosis drug development? A systematic review and meta-analysis. eBioMedicine. 2024;110. doi:10.1016/j.ebiom.2024.105434

Thomas Hartung. The (misleading) role of animal models in drug development. Frontiers in Drug Discovery. 2024;4. doi:10.3389/fddsv.2024.1355044

Guiyoung Park, Yeri Alice Rim, Yeowon Sohn, Yoojun Nam, Ji Hyeon Ju. Replacing Animal Testing with Stem Cell-Organoids : Advantages and Limitations. Stem Cell Reviews and Reports. 2024. doi:10.1007/s12015-024-10723-5

Ana Ubago-Rodríguez, María I. Quiñones-Vico, Manuel Sánchez-Díaz, et al. Challenges in Psoriasis Research: A Systematic Review of Preclinical Models. Dermatology. 2024;240(4):620-652. doi:10.1159/000538993