Translation and validation

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Hamideh Frühwein, Norbert W. Paul. ā€œLost in translation?ā€ Animal research in the era of precision medicine. Journal of Translational Medicine. 2025;23(1):152. doi:10.1186/s12967-025-06084-3
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Thomas Hartung. The (misleading) role of animal models in drug development. Frontiers in Drug Discovery. 2024;4. doi:10.3389/fddsv.2024.1355044
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Feline W. Lindhout, Fenna M. Krienen, Katherine S. Pollard, Madeline A. Lancaster. A molecular and cellular perspective on human brain evolution and tempo. Nature. 2024;630(8017):596-608. doi:10.1038/s41586-024-07521-x
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Guiyoung Park, Yeri Alice Rim, Yeowon Sohn, Yoojun Nam, Ji Hyeon Ju. Replacing Animal Testing with Stem Cell-Organoids: Advantages and Limitations. Stem Cell Reviews and Reports. 2024. doi:10.1007/s12015-024-10723-5
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Manish Sharma, Mukta Nag, Gregory Q. Del Prete. Minimally Modified HIV-1 Infection of Macaques: Development, Utility, and Limitations of Current Models. Viruses. 2024;16(10):1618. doi:10.3390/v16101618
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Alberto Granzotto, Bryce Vissel, Stefano L Sensi. Lost in translation: Inconvenient truths on the utility of mouse models in Alzheimer’s disease research. Timothy E Behrens, ed. eLife. 2024;13:e90633. doi:10.7554/eLife.90633
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Sofia Batista Leite, Matthew Brooke, Annamaria Carusi, et al. Promoting Reusable and Open Methods and Protocols (PRO-MaP): Draft Recommendations to Improve Methodological Clarity in Life Sciences Publications.; 2024. https://osf.io/preprints/osf/x85gh.
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Lindsay J. Marshall, Kathleen M. Conlee. The case of the missing mouse—developing cystic fibrosis drugs without using animals. Frontiers in Drug Discovery. 2024;4. doi:10.3389/fddsv.2024.1347246
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Ivana Jaric, Bernhard Voelkl, Irmgard Amrein, et al. Using mice from different breeding sites fails to improve replicability of results from single-laboratory studies. Lab Animal. 2024;53:18-22. doi:10.1038/s41684-023-01307-w
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Ingrid Berg, Pia Härvelid, Wolfgang Emanuel Zürrer, Marianna Rosso, Daniel S. Reich, Benjamin Victor Ineichen. Which experimental factors govern successful animal-to-human translation in multiple sclerosis drug development? A systematic review and meta-analysis. eBioMedicine. 2024;110. doi:10.1016/j.ebiom.2024.105434
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