Reviews and perspectives

Surat Parvatam, David Pamies, Francesca Pistollato, et al. Taking the leap toward human-specific nonanimal methodologies: The need for harmonizing global policies for microphysiological systems. Stem Cell Reports. 2024;19(1):37-40. doi:10.1016/j.stemcr.2023.11.008

Hui Wang, Xiufan Ning, Feng Zhao, Hui Zhao, Dong Li. Human organoids-on-chips for biomedical research and applications. Theranostics. 2024;14(2):788. doi:10.7150/thno.90492

Lena Smirnova, Thomas Hartung. The Promise and Potential of Brain Organoids. Advanced Healthcare Materials. 2024:2302745. doi:10.1002/adhm.202302745

Derrick Butler, Darwin R. Reyes. Heart-on-a-chip systems: disease modeling and drug screening applications. Lab on a Chip. 2024;24(5):1494-1528. doi:10.1039/D3LC00829K

Mauricio Goncalves da Costa Sousa, Sofia M. Vignolo, Cristiane Miranda Franca, et al. Engineering models of head and neck and oral cancers on-a-chip. Biomicrofluidics. 2024;18:021502. doi:10.1063/5.0186722

Caitlin Lynch, Srilatha Sakamuru, Masato Ooka, et al. High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions. Annual Review of Pharmacology and Toxicology. 2024;64(Volume 64, 2024):191-209. doi:10.1146/annurev-pharmtox-112122-104310

John Parascandola. A History of the Development of Alternatives to Animals in Research and Testing. In: New Directions in the Human-Animal Bond. West Layfayette: Purdue University Press; 2024. https://docs.lib.purdue.edu/ndhab/7.

Jonas Cerneckis, Hongxia Cai, Yanhong Shi. Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications. Signal Transduction and Targeted Therapy. 2024;9(1):1-26. doi:10.1038/s41392-024-01809-0

Aparna Bhaduri. Chimeric brain organoids capture human genetic diversity. Nature. 2024;631(8019):32-33. https://www.nature.com/articles/d41586-024-01648-7.

Oscar J. Abilez. Developing advanced organoids: challenges, progress, and outlook. BioTechniques. 2024;76(12):575-580. doi:10.1080/07366205.2024.2442825