Nervous system

1.
Camiel C. A. Mannens, Lijuan Hu, Peter Lönnerberg, et al. Chromatin accessibility during human first-trimester neurodevelopment. Nature. 2025;647(8088):179-186. doi:10.1038/s41586-024-07234-1
View Full Reference
1.
Li Wang, Cheng Wang, Juan A. Moriano, et al. Molecular and cellular dynamics of the developing human neocortex. Nature. 2025;647(8088):169-178. doi:10.1038/s41586-024-08351-7
View Full Reference
1.
Matthew G. Keefe, Marilyn R. Steyert, Tomasz J. Nowakowski. Lineage-resolved atlas of the developing human cortex. Nature. 2025;647(8088):194-202. doi:10.1038/s41586-025-09033-8
View Full Reference
1.
Boning Qiu, Sara Pompe, Katerina T. Xenaki, et al. Generation of a perfusable three-dimensional human neurovascular chip to model brain drug delivery and immune cell extravasation. Journal of Controlled Release. 2025;387:114257. doi:10.1016/j.jconrel.2025.114257
View Full Reference
1.
James G. Shamul, Zhiyuan Wang, Hyeyeon Gong, et al. Meta-analysis of the make-up and properties of in vitro models of the healthy and diseased blood–brain barrier. Nature Biomedical Engineering. 2025;9(4):566-598. doi:10.1038/s41551-024-01250-2
View Full Reference
1.
Judit González-Gallego, Katalin Todorov-Völgyi, Stephan A. Müller, et al. A fully iPS-cell-derived 3D model of the human blood–brain barrier for exploring neurovascular disease mechanisms and therapeutic interventions. Nature Neuroscience. 2025:1-14. doi:10.1038/s41593-025-02123-w
View Full Reference
1.
Isabel Turpin-Moreno, Adriana Modrego, Andrea Martí-Sarrias, et al. Variability vs. phenotype: Multimodal analysis of Dravet syndrome brain organoids powered by deep learning. iScience. 2025;28(11). doi:10.1016/j.isci.2025.113831
View Full Reference
1.
Chunhui Tian, Zheng Ao, Jonas Cerneckis, et al. Understanding monocyte-driven neuroinflammation in Alzheimer’s disease using human cortical organoid microphysiological systems. Science Advances. 2025;11(34):eadu2708. doi:10.1126/sciadv.adu2708
View Full Reference
1.
Adrià Casamitjana, Matteo Mancini, Eleanor Robinson, et al. A probabilistic histological atlas of the human brain for MRI segmentation. Nature. 2025:1-8. doi:10.1038/s41586-025-09708-2
View Full Reference
1.
Tjitse van der Molen, Alex Spaeth, Mattia Chini, et al. Preconfigured neuronal firing sequences in human brain organoids. Nature Neuroscience. 2025:1-13. doi:10.1038/s41593-025-02111-0
View Full Reference