1.
Kai Cheng, Autumn Williams, Anannya Kshirsagar, et al. Machine learning-enabled detection of electrophysiological signatures in iPSC-derived models of schizophrenia and bipolar disorder. APL Bioengineering. 2025;9(3):036118. doi:10.1063/5.0250559
Nervous system
1.
Dowlette-Mary Alam El Din, Leah Moenkemoeller, Alon Loeffler, et al. Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory. Communications Biology. 2025;8(1):1237. doi:10.1038/s42003-025-08632-5
1.
Dowlette-Mary Alam El Din, Leah Moenkemoeller, Alon Loeffler, et al. Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory. Communications Biology. 2025;8(1):1237. doi:10.1038/s42003-025-08632-5
1.
Kai Cheng, Anannya Kshirsagar, John Nixon, et al. Model systems for emulating human tissue and physiology in psychiatric research. Frontiers in Neuroscience. 2025;19:1527826. doi:10.3389/fnins.2025.1527826
1.
Dana M. Cairns, Brooke M. Smiley, Jordan A. Smiley, et al. Repetitive injury induces phenotypes associated with Alzheimer’s disease by reactivating HSV-1 in a human brain tissue model. Science Signaling. 2025;18(868):eado6430. doi:10.1126/scisignal.ado6430
1.
Aakash Patel, Suruchi Poddar, Daniel Nierenberg, et al. Microphysiological system to address the opioid crisis: A novel multi-organ model of acute opioid overdose and recovery. Current Research in Toxicology. 2025;8:100209. doi:10.1016/j.crtox.2024.100209
1.
Xianwei Chen, Guoqiang Sun, Lizhao Feng, E. Tian, Yanhong Shi. Human iPSC-derived microglial cells protect neurons from neurodegeneration in long-term cultured adhesion brain organoids. Communications Biology. 2025;8(1):1-11. doi:10.1038/s42003-024-07401-0
1.
Anna Pagliaro, Francesco Andreatta, Roxy Finger, Benedetta Artegiani, Delilah Hendriks. Generation of human fetal brain organoids and their CRISPR engineering for brain tumor modeling. Nature Protocols. 2025:1-38. doi:10.1038/s41596-024-01107-7
1.
Anna Pagliaro, Francesco Andreatta, Roxy Finger, Benedetta Artegiani, Delilah Hendriks. Generation of human fetal brain organoids and their CRISPR engineering for brain tumor modeling. Nature Protocols. 2025:1-38. doi:10.1038/s41596-024-01107-7
1.
Gulimiheranmu Maisumu, Stephanie Willerth, Michael Nestor, et al. Brain organoids: building higher-order complexity and neural circuitry models. Trends in Biotechnology. 2025. doi:10.1016/j.tibtech.2025.02.009