Nervous system

Andrew N. Shen, Katelin S. Matazel, W. Drew Gill, Lorna Ewart, Randy S. Daughters, Hector Rosas-Hernandez. Modeling neurovascular dysfunction in Alzheimer’s disease using an isogenic brain-chip model. Fluids and Barriers of the CNS. 2026;23(1):1. doi:10.1186/s12987-025-00708-y

Ami Mehta-Doshi, Blake L. Tsu, Consuelo Sauceda, et al. Age-dependent neuroinflammatory effects of red blood cells and their exosomes in a human brain-on-chip model. Blood Red Cells & Iron. 2026;2(1):100044. doi:10.1016/j.brci.2025.100044

Dowlette-Mary Alam El Din, Leah Moenkemoeller, Alon Loeffler, et al. Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory. Communications Biology. 2025;8(1):1237. doi:10.1038/s42003-025-08632-5

Ji-il Kim, Kent Imaizumi, Ovidiu Jurjuț, et al. Human assembloid model of the ascending neural sensory pathway. Nature. 2025:1-11. doi:10.1038/s41586-025-08808-3

Dowlette-Mary Alam El Din, Leah Moenkemoeller, Alon Loeffler, et al. Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory. Communications Biology. 2025;8(1):1237. doi:10.1038/s42003-025-08632-5

Kai Cheng, Autumn Williams, Anannya Kshirsagar, et al. Machine learning-enabled detection of electrophysiological signatures in iPSC-derived models of schizophrenia and bipolar disorder. APL Bioengineering. 2025;9(3):036118. doi:10.1063/5.0250559

Catarina M. Gomes, Daniel Simão, Carolina Cardoso Gonçalves, et al. Addressing neuroinflammation in human induced pluripotent stem cell-derived central nervous system neurospheroids. iScience. 2025;28(9). doi:10.1016/j.isci.2025.113246

Anannya Kshirsagar, Hayk Mnatsakanyan, Sai Kulkarni, et al. Multi-Region Brain Organoids Integrating Cerebral, Mid-Hindbrain, and Endothelial Systems. Advanced Science. 2025;12(33):e03768. doi:10.1002/advs.202503768

Laura Castro-Aldrete, Melanie Einsiedler, Carla Cuní-López, et al. Modelling sex differences of neurological disorders in vitro. Nature Reviews Bioengineering. 2025:1-22. doi:10.1038/s44222-025-00355-w

Hyehyun Kim, Gregory Girardi, Allison Pickle, Testaverde S. Kim, Erkin Seker. Microfluidic tools to model, monitor, and modulate the gut–brain axis. Biomicrofluidics. 2025;19(2):021301. doi:10.1063/5.0253041