1.
Smriti Mallapaty. The mini lungs and other organoids helping to beat COVID. Nature. 2021;593(7860):492-494. doi:10.1038/d41586-021-01395-z
Immune/infectious disease
1.
Partho Protim Adhikary, Qurrat Ul Ain, Andreas Christian Hocke, Sarah Hedtrich. COVID-19 highlights the model dilemma in biomedical research. Nature Reviews Materials. 2021;6(5):374-376. doi:10.1038/s41578-021-00305-z
1.
Min Zhang, Peng Wang, Ronghua Luo, et al. Biomimetic Human Disease Model of SARS-CoV-2-Induced Lung Injury and Immune Responses on Organ Chip System. Advanced Science. 2021;8(3):2002928. doi:10.1002/advs.202002928
1.
Kevin G. Chen, Kyeyoon Park, Jason R. Spence. Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids. Nature Cell Biology. 2021;23(8):822-833. doi:10.1038/s41556-021-00721-x
1.
Christopher Hopkins, Chidinma Onweni, Victoria Zambito, et al. Platforms for Personalized Polytherapeutics Discovery in COVID-19. Journal of Molecular Biology. 2021;433(10):166945. doi:10.1016/j.jmb.2021.166945
1.
Yaqing Wang, Peng Wang, Jianhua Qin. Microfluidic Organs-on-a-Chip for Modeling Human Infectious Diseases. Accounts of Chemical Research. 2021;54(18):3550-3562. doi:10.1021/acs.accounts.1c00411
1.
Longlong Si, Haiqing Bai, Melissa Rodas, et al. A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics. Nature Biomedical Engineering. 2021;5(8):815-829. doi:10.1038/s41551-021-00718-9
1.
Argus M. Sun, Tyler Hoffman, Bao Q. Luu, Nureddin Ashammakhi, Song Li. Application of lung microphysiological systems to COVID-19 modeling and drug discovery: a review. Bio-Design and Manufacturing. 2021;4(4):757-775. doi:10.1007/s42242-021-00136-5
1.
Bérénice Charrez, Verena Charwat, Brian A. Siemons, et al. Heart Muscle Microphysiological System for Cardiac Liability Prediction of Repurposed COVID-19 Therapeutics. Frontiers in Pharmacology. 2021;12:684252. doi:10.3389/fphar.2021.684252
1.
Louisa Helms, Silvia Marchiano, Ian B. Stanaway, et al. Cross-validation of SARS-CoV-2 responses in kidney organoids and clinical populations. JCI insight. 2021;6(24):e154882. doi:10.1172/jci.insight.154882