Immune/infectious disease

Gabriela S. Kronemberger, Fabiana A. Carneiro, Danielle F. Rezende, Leandra S. Baptista. Spheroids and organoids as humanized 3D scaffold-free engineered tissues for SARS-CoV-2 viral infection and drug screening. Artificial Organs. 2021;45(6):548-558. doi:10.1111/aor.13880

Yuling Han, Xiaohua Duan, Liuliu Yang, et al. Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. Nature. 2021;589(7841):270-275. doi:10.1038/s41586-020-2901-9

Miriane de Oliveira, Maria T. De Sibio, Felipe A. S. Costa, Marna E. Sakalem. Airway and Alveoli Organoids as Valuable Research Tools in COVID-19. ACS Biomaterials Science & Engineering. 2021;7(8):3487-3502. doi:10.1021/acsbiomaterials.1c00306

Bruna A. G. de Melo, Julia C. Benincasa, Elisa M. Cruz, Juliana Terzi Maricato, Marimelia A. Porcionatto. 3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to bioprinting. Biomedical Journal. 2021;44(1):31-42. doi:10.1016/j.bj.2020.11.009

Argus M. Sun, Tyler Hoffman, Bao Q. Luu, Nureddin Ashammakhi, Song Li. Application of lung microphysiological systems to COVID-19 modeling and drug discovery: a review. Bio-Design and Manufacturing. 2021;4(4):757-775. doi:10.1007/s42242-021-00136-5

Mart M. Lamers, Tim I. Breugem, Anna Z. Mykytyn, et al. Human organoid systems reveal in vitro correlates of fitness for SARS-CoV-2 B.1.1.7. 2021:2021.05.03.441080. doi:10.1101/2021.05.03.441080

Alice Maria Giani, Shuibing Chen. Human pluripotent stem cell-based organoids and cell platforms for modelling SARS-CoV-2 infection and drug discovery. Stem Cell Research. 2021;53:102207. doi:10.1016/j.scr.2021.102207

Jelte van der Vaart, Mart M. Lamers, Bart L. Haagmans, Hans Clevers. Advancing lung organoids for COVID-19 research. Disease Models & Mechanisms. 2021;14(6):dmm049060. doi:10.1242/dmm.049060

Vivek V. Thacker, Kunal Sharma, Neeraj Dhar, Gian-Filippo Mancini, Jessica Sordet-Dessimoz, John D. McKinney. Rapid endotheliitis and vascular damage characterize SARS-CoV-2 infection in a human lung-on-chip model. EMBO reports. 2021;22(6):e52744. doi:10.15252/embr.202152744

A. L. Gard, R. J. Luu, C. R. Miller, et al. High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro. Scientific Reports. 2021;11(1):14961. doi:10.1038/s41598-021-94095-7