Immune/infectious disease

Lena Gauthier, Hristina Koceva, Yann Bachelot, et al. Generation of an Induced Pluripotent Stem Cell-Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments. Advanced Healthcare Materials. 2026;15(11):e05141. doi:10.1002/adhm.202405141

Johanna Friederike Steffen, Lina Widerspick, Stephanie Jansen, Dennis Tappe. A human cerebral organoid model of West Nile virus encephalitis shows innate immunocompetency. Nature Communications. 2026;17(1):2318. doi:10.1038/s41467-026-70281-x

Karen Hoffmann, Ulrike Behrendt, Peter Pennitz, et al. Mechanical strain exacerbates <i>Pseudomonas</i> infection in an organoid-based pneumonia-on-a-chip model. The Journal of Clinical Investigation. 2026;136(2). doi:10.1172/JCI192454

Nathalia Almeida, Sam Acors, Daniel Cox, et al. Generation and characterization of iPSC models from HIV-1-positive individuals with divergent clinical outcomes. Stem Cell Reports. 2026. doi:10.1016/j.stemcr.2025.102786

Anna Niarakis, Gary An, Luiz Ladeira, et al. Building Immune Digital Twins: An International and Transdisciplinary Community Effort. ImmunoInformatics. 2025. doi:10.1016/j.immuno.2025.100060

Jonas Jäger, Maria Thon, Katharina Schimek, Uwe Marx, Susan Gibbs, Jasper J. Koning. Differential biomarker expression of blood and lymphatic vasculature in multi-organ-chips. Scientific Reports. 2025;15(1):14492. doi:10.1038/s41598-025-96367-y

Andrew I. Morrison, Jonas Jäger, Charlotte M. de Winde, et al. Integration of lymphatic vasculature to a human lymph node-on-chip enhances physiological immune properties. Materials Today Bio. 2025;35:102326. doi:10.1016/j.mtbio.2025.102326

Rachel Ringquist, Eshant Bhatia, Paramita Chatterjee, et al. An immune-competent lung-on-a-chip for modelling the human severe influenza infection response. Nature Biomedical Engineering. 2025:1-23. doi:10.1038/s41551-025-01491-9

Keitaro Kanie, Takeshi Ito, Genzo Iguchi, et al. Modeling of T cell-mediated autoimmune pituitary disease using human induced pluripotent stem cell-originated organoid. Nature Communications. 2025;16(1):7900. doi:10.1038/s41467-025-63183-x

Xin Chen, Mustafa Ghanizada, Vamsee Mallajosyula, et al. Differential roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses. Nature Immunology. 2025:1-10. doi:10.1038/s41590-024-02062-x