Cancer

Laura Rüland, Francesco Andreatta, Simone Massalini, et al. Organoid models of fibrolamellar carcinoma mutations reveal hepatocyte transdifferentiation through cooperative BAP1 and PRKAR2A loss. Nature Communications. 2023;14(1):2377. doi:10.1038/s41467-023-37951-6

Abdullah O. Khan, Antonio Rodriguez-Romera, Jasmeet S. Reyat, et al. Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies. Cancer Discovery. 2023;13(2):364-385. doi:10.1158/2159-8290.CD-22-0199

Elena Kromidas, Alicia Geier, Adrian Weghofer, Hui-Yu Liu, Martin Weiss, Peter Loskill. Immunocompetent PDMS-Free Organ-on-Chip Model of Cervical Cancer Integrating Patient-Specific Cervical Fibroblasts and Neutrophils. Advanced Healthcare Materials. 2023:2302714. doi:10.1002/adhm.202302714

Naira Baregamian, Konjeti R. Sekhar, Evan S. Krystofiak, et al. Engineering functional 3-dimensional patient-derived endocrine organoids for broad multiplatform applications. Surgery. 2023;173(1):67-75. doi:10.1016/j.surg.2022.09.027

Zhen Fang, Peijuan Li, Fengying Du, Liang Shang, Leping Li. The role of organoids in cancer research. Experimental Hematology & Oncology. 2023;12(1):69. doi:10.1186/s40164-023-00433-y

Xuexue Xie, Xinyu Li, Wei Song. Tumor organoid biobank-new platform for medical research. Scientific Reports. 2023;13(1):1819. doi:10.1038/s41598-023-29065-2

Burcu Firatligil-Yildirir, Ozden Yalcin-Ozuysal, null Nonappa. Recent advances in lab-on-a-chip systems for breast cancer metastasis research. Nanoscale Advances. 2023;5(9):2375-2393. doi:10.1039/d2na00823h

Lisa Asciak, Lauren Gilmour, Jonathan A. Williams, et al. Investigating multi-material hydrogel three-dimensional printing for in vitro representation of the neo-vasculature of solid tumours: a comprehensive mechanical analysis and assessment of nitric oxide release from human umbilical vein endothelial cells. Royal Society Open Science. 2023;10(8):230929. doi:10.1098/rsos.230929

Sive Mullen, Dania Movia. The role of extracellular vesicles in non-small-cell lung cancer, the unknowns, and how new approach methodologies can support new knowledge generation in the field. European Journal of Pharmaceutical Sciences. 2023;188:106516. doi:10.1016/j.ejps.2023.106516

Sean Hockney, Jessica Parker, Jasmin E. Turner, et al. Next generation organoid engineering to replace animals in cancer drug testing. Biochemical Pharmacology. 2023;213:115586. doi:10.1016/j.bcp.2023.115586