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A human 3D immune competent full-thickness skin model mimicking dermal dendritic cell activation
ReferenceJohanna Maria Hölken , Katja Friedrich , Marion Merkel , Nelli Blasius , Ursula Engels , Timo Buhl , Karsten Rüdiger Mewes , Lars Vierkotten , Nicole Elisabeth Teusch Frontiers in Immunology. 2023;14. doi: 10.3389/fimmu.2023.1276151 We have integrated …
An in vitro assay for toxicity testing of Clostridium perfringens type C β-toxin
ReferenceMarieke Hoonakker , Afshin Zariri , Lisette de Brouwer , Dionne David , Anouska Borgman , Arjen Sloots Frontiers in Immunology. 2024;15. doi: 10.3389/fimmu.2024.1373411 IntroductionVeterinary vaccines against Clostridium …
An in silico modeling approach to understanding the dynamics of the post-burn immune response
ReferenceH. Ibrahim Korkmaz , Vivek M. Sheraton , Roland V. Bumbuc , Meifang Li , Anouk Pijpe , Patrick P. G. Mulder , Bouke K. H. L. Boekema , Evelien de Jong , Stephan G. F. Papendorp , Ruud Brands , Esther Middelkoop , Peter M. A. Sloot , Paul P. M. van Zuijlen …
Advances in phage display based nano immunosensors for cholera toxin
ReferenceYang Li , Kai-di Yang , De-cai Kong , Jun-feng Ye Frontiers in Immunology. 2023;14. doi: 10.3389/fimmu.2023.1224397 Cholera, a persistent global public health concern, continues to cause outbreaks in approximately 30 countries and territories this …
In vitro immunity: an overview of immunocompetent organ-on-chip models
ReferenceAndrew I. Morrison , Mirthe J. Sjoerds , Leander A. Vonk , Susan Gibbs , Jasper J. Koning Frontiers in Immunology. 2024;15. doi: 10.3389/fimmu.2024.1373186 Impressive advances have been made to replicate human physiology in vitro over …
Alternative in vitro models used in the main safety tests of cosmetic products and new challenges
ReferenceEdith Filaire , Rachida Nachat-Kappes , Camille Laporte , Marie-Françoise Harmand , Marina Simon , Christian Poinsot International Journal of Cosmetic Science. 2022;44(6):604-613. doi: 10.1111/ics.12803 Background Guided by ethical considerations and …
Immune-competent <i>in vitro</i> co-culture models as an approach for skin sensitisation assessment
ReferenceAmélie Thélu , Sophie Catoire , Saadia Kerdine-Römer Toxicology in Vitro. 2020;62:104691. doi: 10.1016/j.tiv.2019.104691 There is a complex interplay between numerous cell types that act at different steps of the mechanism leading to allergic contact …
3D biofabrication of diseased human skin models in vitro
ReferenceMinjun Ahn , Won-Woo Cho , Wonbin Park , Jae-Seong Lee , Min-Ju Choi , Qiqi Gao , Ge Gao , Dong-Woo Cho , Byoung Soo Kim Biomaterials Research. 2023;27(1):80. doi: 10.1186/s40824-023-00415-5 Human skin is an organ located in the outermost part of the …
Recent Developments in 3D Bio-Printing and Its Biomedical Applications
ReferenceHumira Assad , Arvina Assad , Ashish Kumar Pharmaceutics. 2023;15(1):255. doi: 10.3390/pharmaceutics15010255 The fast-developing field of 3D bio-printing has been extensively used to improve the usability and performance of scaffolds filled with cells. …
High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions
ReferenceCaitlin Lynch , Srilatha Sakamuru , Masato Ooka , Ruili Huang , Carleen Klumpp-Thomas , Paul Shinn , David Gerhold , Anna Rossoshek , Sam Michael , Warren Casey , Michael F. Santillo , Suzanne Fitzpatrick , Russell S. Thomas , Anton Simeonov , Menghang …