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Race in biological and biomedical research
ReferenceRichard S. Cooper Cold Spring Harbor Perspectives in Medicine. 2013;3(11):a008573. doi: 10.1101/cshperspect.a008573 The concept of race has had a significant influence on research in human biology since the early 19th century. But race was given its …
Ancestry-dependent gene expression correlates with reprogramming to pluripotency and multiple dynamic biological processes
ReferenceLaura S. Bisogno , Jun Yang , Brian D. Bennett , James M. Ward , Lantz C. Mackey , Lois A. Annab , Pierre R. Bushel , Sandeep Singhal , Shepherd H. Schurman , Jung S. Byun , Anna MarÃa Nápoles , Eliseo J. Pérez-Stable , David C. Fargo , Kevin Gardner , …
Chromatin Accessibility Landscape of Human Triple-negative Breast Cancer Cell Lines Reveals Variation by Patient Donor Ancestry
ReferenceAlexandra R. Harris , Gatikrushna Panigrahi , Huaitian Liu , Vishal N. Koparde , Maeve Bailey-Whyte , Tiffany H. Dorsey , Clayton C. Yates , Stefan Ambs Cancer Research Communications. 2023;3(10):2014-2029. doi: 10.1158/2767-9764.CRC-23-0236 African …
Human iPSC-derived microglial cells protect neurons from neurodegeneration in long-term cultured adhesion brain organoids
ReferenceXianwei Chen , Guoqiang Sun , Lizhao Feng , E. Tian , Yanhong Shi Communications Biology. 2025;8(1):1-11. doi: 10.1038/s42003-024-07401-0 Brain organoid models have greatly facilitated our understanding of human brain development and disease. However, key …
Bridging imaging-based in vitro methods from biomedical research to regulatory toxicology
ReferenceMonica Piergiovanni , Milena Mennecozzi , Erio Barale-Thomas , Davide Danovi , Sebastian Dunst , David Egan , Aurora Fassi , Matthew Hartley , Philipp Kainz , Katharina Koch , Sylvia E. Le Dévédec , Iris Mangas , Elena Miranda , Jo Nyffeler , Enrico …
Journeying Through Journals: The Publishing Process and How to Maximise Research Impact
ReferenceJudith C. Madden , Helena Kandarova , Winfried Neuhaus , Nikki Osborne , Alicia Paini , Rita Seabra , Susan Trigwell Alternatives to Laboratory Animals. 2024;52(6):334-351. doi: 10.1177/02611929241286624 Publication is essential to share new ideas, …
Developing advanced organoids: challenges, progress, and outlook
ReferenceOscar J. Abilez BioTechniques. 2024;76(12):575-580. doi: 10.1080/07366205.2024.2442825 https://www.tandfonline.com/doi/full/10.1080/07366205.2024.2442825 Library Collection(s) Reviews and perspectives Download Citation BibTeX EndNote X3 XML EndNote 7 XML …
Impact of psychological stressors on natural killer cell function: A comprehensive analysis based on stressor type, duration, intensity, and species
ReferenceAlexis R. Katz , Margaret P. Huntwork , Jay K. Kolls , Jenny L. Hewes , Calder R. Ellsworth , Robert D. E. Clark , John C. Carlson Physiology & Behavior. 2025;288:114734. doi: 10.1016/j.physbeh.2024.114734 Patients with natural killer (NK) cell deficiency …
Generation of human fetal brain organoids and their CRISPR engineering for brain tumor modeling
ReferenceAnna Pagliaro , Francesco Andreatta , Roxy Finger , Benedetta Artegiani , Delilah Hendriks Nature Protocols. 2025:1-38. doi: 10.1038/s41596-024-01107-7 The developing human brain displays unique features that are difficult to study in animal models. …
Digital twin-enhanced three-organ microphysiological system for studying drug pharmacokinetics in pregnant women
ReferenceKatja Graf , José Martin Murrieta-Coxca , Tobias Vogt , Sophie Besser , Daria Geilen , Tim Kaden , Anne-Katrin Bothe , Diana Maria Morales-Prieto , Behnam Amiri , Stephan Schaller , Ligaya Kaufmann , Martin Raasch , Ramy M. Ammar , Christian Maass …