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Organoid Modeling of the Tumor Immune Microenvironment
ReferenceJames T. Neal , Xingnan Li , Junjie Zhu , Valeria Giangarra , Caitlin L. Grzeskowiak , Jihang Ju , Iris H. Liu , Shin-Heng Chiou , Ameen A. Salahudeen , Amber R. Smith , Brian C. Deutsch , Lillian Liao , Allison J. Zemek , Fan Zhao , Kasper Karlsson , …
Progress and opportunities for tissue-engineered skin
ReferenceSheila MacNeil Nature. 2007;445(7130):874-880. doi: 10.1038/nature05664 Tissue-engineered skin is now a reality. For patients with extensive full-thickness burns, laboratory expansion of skin cells to achieve barrier function can make the difference …
Pump-less, recirculating organ-on-a-chip (rOoC) platform
ReferenceMathias Busek , Aleksandra Aizenshtadt , Timo Koch , Anna Frank , Ludivine Delon , Mikel Amirola Martinez , Alexey Golovin , Clotilde Dumas , Justyna Stokowiec , Stefan Gruenzner , Espen Melum , Stefan Krauss Lab on a Chip. 2023;23(4):591-608. doi: …
Progenitor identification and SARS-CoV-2 infection in human distal lung organoids
ReferenceAmeen A. Salahudeen , Shannon S. Choi , Arjun Rustagi , Junjie Zhu , Vincent van Unen , Sean M. de la O , Ryan A. Flynn , Mar Margalef-Català , António J. M. Santos , Jihang Ju , Arpit Batish , Tatsuya Usui , Grace X. Y. Zheng , Caitlin E. Edwards , Lisa …
The Application of Organs-on-a-Chip in Dental, Oral, and Craniofacial Research
ReferenceC. Huang , F. Sanaei , W.P.R. Verdurmen , F. Yang , W. Ji , X. F. Walboomers Journal of Dental Research. 2023;102(4):364-375. doi: 10.1177/00220345221145555 The current development of microfluidics-based microphysiological systems (MPSs) will rapidly lead …
Tumor organoid biobank-new platform for medical research
ReferenceXuexue Xie , Xinyu Li , Wei Song Scientific Reports. 2023;13(1):1819. doi: 10.1038/s41598-023-29065-2 Organoids are a new type of 3D model for tumor research, which makes up for the shortcomings of cell lines and xenograft models, and promotes the …
Progress toward ‘bone-on-a-chip’
ReferenceRobert Phillips Nature Reviews Rheumatology. 2023:1-1. doi: 10.1038/s41584-023-00998-2 Researchers have co-cultured human mesenchymal stromal cells and monocytes to generate bone-like structures that have the potential to facilitate the study of bone …
Suggesting Reviewers
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Suggesting Reviewers At the editorial and peer review stages, animal methods bias may result in a lengthy revision period or ultimately rejection if authors fail to comply with requests for animal experiments. To help minimize these undesirable outcomes, …
Young TPI Impact Workshop
Event
Young TPI Impact Workshop Thursday, October 31 2024, 12:30 - 7:30pm CET (7:30am - 2:30pm EDT) Calling all early-career researchers! Are you ready to amplify the impact of your research in the transition to animal-free innovation? Join us for the Young TPI …
3Rs Training Webinar: Addressing Reviewers’ Preference for Animal-Based Methods
Event
3Rs Training Webinar: Addressing Reviewers’ Preference for Animal-Based Methods Wednesday, December 18 2024, 1 - 2:30pm EST The next 3Rs Training Webinar hosted by the Johns Hopkins University Center for Alternatives to Animal Testing (CAAT) and the …