Single cell sequencing analysis of respiratory syncytial virus–infected pediatric and adult human nose organoids reveals age differences, proliferative diversity and identifies novel cellular tropism

Anubama Rajan, Divya Nagaraj, Carolyn Bomidi, Gina M. Aloisio, Ashley M. Murray, Emily M. Schultz, Amal Kambal, Mary K. Estes, Erin Nicholson, Vasanthi Avadhanula, Sarah E. Blutt, Pedro A. Piedra

Journal of Infection. 2025;91(4). doi: 10.1016/j.jinf.2025.106617

https://www.journalofinfection.com/article/S0163-4453(25)00217-8/fulltext

Keywords

Adult and Pediatric HNO

Human nose organoid

Single cell RNA seq

Library Collection(s)

Immune/infectious disease