Risk Assessment

Jacintha Shenton, Imein Bousnina, Michael Oropallo, et al. Opportunities and insights from pharmaceutical companies on the current use of new approach methodologies in nonclinical safety assessment. Drug Discovery Today. 2025;30(4):104328. doi:10.1016/j.drudis.2025.104328

Maria T. Baltazar, Sophie Cable, Richard Cubberley, et al. Making safety decisions for a sunscreen active ingredient using next-generation risk assessment: Benzophenone-4 case study. ALTEX. 2025;42(3):511-530. doi:10.14573/altex.2501201

Nicole Kleinstreuer, Thomas Hartung. Artificial intelligence (AI)-it’s the end of the tox as we know it (and I feel fine). Archives of Toxicology. 2024. doi:10.1007/s00204-023-03666-2

Marie Corradi, Thomas Luechtefeld, Alyanne M. de Haan, et al. The application of natural language processing for the extraction of mechanistic information in toxicology. Frontiers in Toxicology. 2024;6. doi:10.3389/ftox.2024.1393662

Breanne Kincaid, Przemyslaw Piechota, Emily Golden, Mikhail Maertens, Thomas Hartung, Alexandra Maertens. Using in silico tools to predict flame retardant metabolites for more informative exposomics-based approaches. Frontiers in Toxicology. 2023;5:1216802. doi:10.3389/ftox.2023.1216802

Anna J. van der Zalm, João Barroso, Patience Browne, et al. A framework for establishing scientific confidence in new approach methodologies. Archives of Toxicology. 2022;96:2865-2879. doi:10.1007/s00204-022-03365-4

Taha Messelmani, Lisa Morisseau, Yasuyuki Sakai, et al. Liver organ-on-chip models for toxicity studies and risk assessment. Lab on a Chip. 2022;22(13):2423-2450. doi:10.1039/d2lc00307d

Daniel Krewski, Patrick Saunders-Hastings, Robert A. Baan, et al. Development of an Evidence-Based Risk Assessment Framework. ALTEX. 2022;39(4):667-693. doi:10.14573/altex.2004041

Daniel Krewski, Patrick Saunders-Hastings, Robert A. Baan, et al. Development of an Evidence-Based Risk Assessment Framework. ALTEX. 2022;39(4):667-693. doi:10.14573/altex.2004041

Sebastian Hoffmann, Paul Whaley, Katya Tsaioun. How evidence-based methodologies can help identify and reduce uncertainty in chemical risk assessment. ALTEX. 2022;39(2):175-182. doi:10.14573/altex.2201131