Reduction

Laura Lotfi, T. William O’Neill, Angela Wilcox, Steven Bulera. Virtual control groups in nonclinical research: A Re-analysis of 20 studies using virtual control group data. Regulatory Toxicology and Pharmacology. 2026;168:106077. doi:10.1016/j.yrtph.2026.106077

Federico Germani, Julian W. März, Alessandro Luciani, Olivier Devuyst, Nikola Biller-Andorno. Ethical and legal considerations of digital animal models: pioneering reduction and replacement. Trends in Biotechnology. 2026;44(3):593-595. doi:10.1016/j.tibtech.2025.08.011