Humans

Fuki Yokoi, Sayaka Deguchi, Kazuo Takayama. Organ-on-a-chip models for elucidating the cellular biology of infectious diseases. Biochimica Et Biophysica Acta. Molecular Cell Research. 2023;1870(6):119504. doi:10.1016/j.bbamcr.2023.119504

Vibeke Fosse, Emanuela Oldoni, Florence Bietrix, et al. Recommendations for robust and reproducible preclinical research in personalised medicine. BMC Medicine. 2023;21:14. doi:10.1186/s12916-022-02719-0

Keren J. Carss, Aimee M. Deaton, Alberto Del Rio-Espinola, et al. Using human genetics to improve safety assessment of therapeutics. Nature Reviews. Drug Discovery. 2023;22(2):145-162. doi:10.1038/s41573-022-00561-w

Stephen Burgess, Amy M. Mason, Andrew J. Grant, et al. Using genetic association data to guide drug discovery and development: Review of methods and applications. American Journal of Human Genetics. 2023;110(2):195-214. doi:10.1016/j.ajhg.2022.12.017

Katerina Trajanoska, Claude Bhérer, Daniel Taliun, Sirui Zhou, J. Brent Richards, Vincent Mooser. From target discovery to clinical drug development with human genetics. Nature. 2023;620(7975):737-745. doi:10.1038/s41586-023-06388-8

Thomas Hartung. ToxAIcology - The evolving role of artificial intelligence in advancing toxicology and modernizing regulatory science. ALTEX. 2023;40(4):559-570. doi:10.14573/altex.2309191

Leqian Yu, Deirdre Logsdon, Carlos A. Pinzon-Arteaga, et al. Large-scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal cross talk. Cell Stem Cell. 2023;30(9):1246-1261.e9. doi:10.1016/j.stem.2023.08.002

Jonas Simon Fleck, Sophie Martina Johanna Jansen, Damian Wollny, et al. Inferring and perturbing cell fate regulomes in human brain organoids. Nature. 2023;621(7978):365-372. doi:10.1038/s41586-022-05279-8

Chong Li, Jonas Simon Fleck, Catarina Martins-Costa, et al. Single-cell brain organoid screening identifies developmental defects in autism. Nature. 2023;621(7978):373-380. doi:10.1038/s41586-023-06473-y

Judy Strickland, Jaleh Abedini, David G. Allen, et al. A database of human predictive patch test data for skin sensitization. Archives of Toxicology. 2023;97(11):2825-2837. doi:10.1007/s00204-023-03530-3