Animals

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Yesl Jun, JaeSeo Lee, Seongkyun Choi, et al. In vivo-mimicking microfluidic perfusion culture of pancreatic islet spheroids. Science Advances. 2019;5(11):eaax4520. doi:10.1126/sciadv.aax4520
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Norman Sachs, Angelos Papaspyropoulos, Domenique D. Zomer-van Ommen, et al. Long-term expanding human airway organoids for disease modeling. The EMBO journal. 2019;38(4):e100300. doi:10.15252/embj.2018100300
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Sabina Kanton, Michael James Boyle, Zhisong He, et al. Organoid single-cell genomic atlas uncovers human-specific features of brain development. Nature. 2019;574(7778):418-422. doi:10.1038/s41586-019-1654-9
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Kathrin Herrmann, Francesca Pistollato, Martin L. Stephens. Beyond the 3Rs: Expanding the use of human-relevant replacement methods in biomedical research. Alternatives to Animal Experimentation. 2019;36(3):343-352. doi:10.14573/altex.1907031
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Sang Hun Lee, SoonGweon Hong, Jihwan Song, et al. Microphysiological Analysis Platform of Pancreatic Islet β-Cell Spheroids. Advanced Healthcare Materials. 2018;7(2). doi:10.1002/adhm.201701111
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Lucy Meigs, Lena Smirnova, Costanza Rovida, Marcel Leist, Thomas Hartung. Animal testing and its alternatives - the most important omics is economics. Alternatives to Animal Experimentation. 2018;35(3):275-305. doi:10.14573/altex.1807041
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Pandora Pound, Merel Ritskes-Hoitinga. Is it possible to overcome issues of external validity in preclinical animal research? Why most animal models are bound to fail. Journal of Translational Medicine. 2018;16(1):304. doi:10.1186/s12967-018-1678-1
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F. Claire Hankenson, James O. Marx, Christopher J. Gordon, John M. David. Effects of Rodent Thermoregulation on Animal Models in the Research Environment. Comparative Medicine. 2018;68(6):425-438. doi:10.30802/AALAS-CM-18-000049
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Norman Sachs, Joep de Ligt, Oded Kopper, et al. A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity. Cell. 2018;172(1-2):373-386.e10. doi:10.1016/j.cell.2017.11.010
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James T. Neal, Xingnan Li, Junjie Zhu, et al. Organoid Modeling of the Tumor Immune Microenvironment. Cell. 2018;175(7):1972-1988.e16. doi:10.1016/j.cell.2018.11.021
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