Animals

Tomasz Kostrzewski, Sophie Snow, Anya Lindström Battle, et al. Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system. Communications Biology. 2021;4(1):1080. doi:10.1038/s42003-021-02616-x

Hyo-Jin Yoon, Yong Jae Lee, Sewoom Baek, et al. Hormone autocrination by vascularized hydrogel delivery of ovary spheroids to rescue ovarian dysfunctions. Science Advances. 2021;7(18):eabe8873. doi:10.1126/sciadv.abe8873

Lucie A. Low, Christine Mummery, Brian R. Berridge, Christopher P. Austin, Danilo A. Tagle. Organs-on-chips: into the next decade. Nature Reviews. Drug Discovery. 2021;20(5):345-361. doi:10.1038/s41573-020-0079-3

Jens Puschhof, Cayetano Pleguezuelos-Manzano, Hans Clevers. Organoids and organs-on-chips: Insights into human gut-microbe interactions. Cell Host & Microbe. 2021;29(6):867-878. doi:10.1016/j.chom.2021.04.002

Valentina Paloschi, Maria Sabater-Lleal, Heleen Middelkamp, et al. Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases. Cardiovascular Research. 2021;117(14):2742-2754. doi:10.1093/cvr/cvab088

Yuling Han, Xiaohua Duan, Liuliu Yang, et al. Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. Nature. 2021;589(7841):270-275. doi:10.1038/s41586-020-2901-9

Rasa Elmentaite, Natsuhiko Kumasaka, Kenny Roberts, et al. Cells of the human intestinal tract mapped across space and time. Nature. 2021;597(7875):250-255. doi:10.1038/s41586-021-03852-1

Ehsanollah Moradi, Sasan Jalili-Firoozinezhad, Mehran Solati-Hashjin. Microfluidic organ-on-a-chip models of human liver tissue. Acta Biomaterialia. 2020;116:67-83. doi:10.1016/j.actbio.2020.08.041

Uwe Marx, Takafumi Akabane, Tommy B. Andersson, et al. Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development. ALTEX. 2020;37(3):365-394. doi:10.14573/altex.2001241

Katherine Groff, David Allen, Warren Casey, Amy Clippinger. Increasing the use of animal-free recombinant antibodies. ALTEX. 2020;37(2):309-311. doi:10.14573/altex.2001071