organ-on-a-chip

Jade Admiraal, Promise O. Emeh, Marleen Bokkers, et al. Building the blood-brain barrier: a scalable self-assembling 3D model of the brain microvasculature under unidirectional flow. Fluids and Barriers of the CNS. 2026;23(1):29. doi:10.1186/s12987-026-00765-x

Matthew Price, Francesca Pistollato. Beyond the amyloid hypothesis: leveraging human-centered complex in vitro models to decode Alzheimer’s disease etiology. Frontiers in Toxicology. 2026;7. doi:10.3389/ftox.2025.1753572

Sanjima Pal, Elee Shimshoni, Salvador Flores Torres, et al. Patient-derived esophageal adenocarcinoma organ chip: a physiologically relevant platform for functional precision oncology. Journal of Translational Medicine. 2025;23(1):577. doi:10.1186/s12967-025-06593-1

Hiroshi Kimura, Masaki Nishikawa, Naokata Kutsuzawa, et al. Advancements in Microphysiological systems: Exploring organoids and organ-on-a-chip technologies in drug development -focus on pharmacokinetics related organs-. Drug Metabolism and Pharmacokinetics. 2025;60:101046. doi:10.1016/j.dmpk.2024.101046

Uwe Marx, Sonja Beken, Zaozao Chen, et al. Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare. ALTEX - Alternatives to animal experimentation. 2025;42(2):204-223. doi:10.14573/altex.2410112

Sayaka Deguchi, Kaori Kosugi, Naoki Takeishi, et al. Construction of multilayered small intestine-like tissue by reproducing interstitial flow. Cell Stem Cell. 2024;31(9):1315-1326.e8. doi:10.1016/j.stem.2024.06.012

Tae Young Kim, Jeong-Won Choi, Kijun Park, et al. Lubricant-Coated Organ-on-a-Chip for Enhanced Precision in Preclinical Drug Testing. Small. 2024:2402431. doi:10.1002/smll.202402431

James I. Kennedy, Scott P. Davies, Peter W. Hewett, et al. Organ-on-a-chip for studying immune cell adhesion to liver sinusoidal endothelial cells: the potential for testing immunotherapies and cell therapy trafficking. Frontiers in Cell and Developmental Biology. 2024;12. doi:10.3389/fcell.2024.1359451

Longjin Zheng, Yang Zhan, Chenxuan Wang, et al. Technological advances and challenges in constructing complex gut organoid systems. Frontiers in Cell and Developmental Biology. 2024;12. doi:10.3389/fcell.2024.1432744

Katy Taylor, Stephanie Modi, Jarrod Bailey. An analysis of trends in the use of animal and non-animal methods in biomedical research and toxicology publications. Frontiers in Lab on a Chip Technologies. 2024;3. doi:10.3389/frlct.2024.1426895