organ-on-a-chip

Ryan Posey, Alican Özkan, Donald E. Ingber. Human organ-on-a-chip technology as a catalyst for drug discovery. Advanced Drug Delivery Reviews. 2026;236:115920. doi:10.1016/j.addr.2026.115920

Matthew Price, Francesca Pistollato. Beyond the amyloid hypothesis: leveraging human-centered complex in vitro models to decode Alzheimer’s disease etiology. Frontiers in Toxicology. 2026;7. doi:10.3389/ftox.2025.1753572

Jade Admiraal, Promise O. Emeh, Marleen Bokkers, et al. Building the blood-brain barrier: a scalable self-assembling 3D model of the brain microvasculature under unidirectional flow. Fluids and Barriers of the CNS. 2026;23(1):29. doi:10.1186/s12987-026-00765-x

Franziska Buck, Jeroen Bugter, Gizem Yorukoglu, Mina Kazemzadeh Dastjerd, Thomas E. Winkler. Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs-On-Chips. Advanced Biology. 2026;10(2):e00536. doi:10.1002/adbi.202500536

Nilanjan Roy, Luca Cucullo. Organs-on-Chips in Drug Development: Engineering Foundations, Artificial Intelligence, and Clinical Translation. Biosensors. 2026;16(3). doi:10.3390/bios16030155

Uwe Marx, Sonja Beken, Zaozao Chen, et al. Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare. ALTEX - Alternatives to animal experimentation. 2025;42(2):204-223. doi:10.14573/altex.2410112

Sanjima Pal, Elee Shimshoni, Salvador Flores Torres, et al. Patient-derived esophageal adenocarcinoma organ chip: a physiologically relevant platform for functional precision oncology. Journal of Translational Medicine. 2025;23(1):577. doi:10.1186/s12967-025-06593-1

Hiroshi Kimura, Masaki Nishikawa, Naokata Kutsuzawa, et al. Advancements in Microphysiological systems: Exploring organoids and organ-on-a-chip technologies in drug development -focus on pharmacokinetics related organs-. Drug Metabolism and Pharmacokinetics. 2025;60:101046. doi:10.1016/j.dmpk.2024.101046

Chao Song, Jiachen Yang, Zhongze Gu. Latest developments of microphysiological systems (MPS) in aging-related and geriatric diseases research: A review. Ageing Research Reviews. 2025;107:102728. doi:10.1016/j.arr.2025.102728

Lindsey K. Huff, Charles M. Amurgis, Lauren E. Kokai, Rosalyn D. Abbott. Optimization and validation of a fat-on-a-chip model for non-invasive therapeutic drug discovery. Frontiers in Bioengineering and Biotechnology. 2024;12. doi:10.3389/fbioe.2024.1404327