Humans

Manuela Cassotta, Hugo Geerts, Lise Harbom, et al. The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible. ALTEX. 2022;39(4):694-709. doi:10.14573/altex.2203161

Anna J. van der Zalm, João Barroso, Patience Browne, et al. A framework for establishing scientific confidence in new approach methodologies. Archives of Toxicology. 2022;96:2865-2879. doi:10.1007/s00204-022-03365-4

Zhong Alan Li, Rocky S. Tuan. Towards establishing human body-on-a-chip systems. Stem Cell Research & Therapy. 2022;13(1):431. doi:10.1186/s13287-022-03130-5

Drew E. Glaser, Matthew B. Curtis, Peter A. Sariano, et al. Organ-on-a-chip model of vascularized human bone marrow niches. Biomaterials. 2022;280:121245. doi:10.1016/j.biomaterials.2021.121245

Claudia Günther, Beate Winner, Markus F. Neurath, Thaddeus S. Stappenbeck. Organoids in gastrointestinal diseases: from experimental models to clinical translation. Gut. 2022;71(9):1892-1908. doi:10.1136/gutjnl-2021-326560

Gui-Wei He, Lin Lin, Jeff DeMartino, et al. Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation. Cell Stem Cell. 2022;29(9):1333-1345.e6. doi:10.1016/j.stem.2022.08.002

Oliver L. Eichmüller, Juergen A. Knoblich. Human cerebral organoids - a new tool for clinical neurology research. Nature Reviews. Neurology. 2022;18(11):661-680. doi:10.1038/s41582-022-00723-9

Shengli Ding, Carolyn Hsu, Zhaohui Wang, et al. Patient-derived micro-organospheres enable clinical precision oncology. Cell Stem Cell. 2022;29(6):905-917.e6. doi:10.1016/j.stem.2022.04.006

Sunghee Estelle Park, Shawn Kang, Jungwook Paek, et al. Geometric engineering of organoid culture for enhanced organogenesis in a dish. Nature Methods. 2022;19(11):1449-1460. doi:10.1038/s41592-022-01643-8

Lorna Ewart, Adrian Roth. Opportunities and challenges with microphysiological systems: a pharma end-user perspective. Nature Reviews. Drug Discovery. 2021;20(5):327-328. doi:10.1038/d41573-020-00030-2