Humans

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Sunghee Estelle Park, Andrei Georgescu, Dongeun Huh. Organoids-on-a-chip. Science (New York, N.Y.). 2019;364(6444):960-965. doi:10.1126/science.aaw7894
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Michael Balls, Jarrod Bailey, Robert D. Combes. How viable are alternatives to animal testing in determining the toxicities of therapeutic drugs? Expert Opinion on Drug Metabolism & Toxicology. 2019;15(12):985-987. doi:10.1080/17425255.2019.1694662
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Jarrod Bailey, Michael Balls. Recent efforts to elucidate the scientific validity of animal-based drug tests by the pharmaceutical industry, pro-testing lobby groups, and animal welfare organisations. BMC Medical Ethics. 2019;20(1):16. doi:10.1186/s12910-019-0352-3
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Sabina Kanton, Michael James Boyle, Zhisong He, et al. Organoid single-cell genomic atlas uncovers human-specific features of brain development. Nature. 2019;574(7778):418-422. doi:10.1038/s41586-019-1654-9
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Elizabeth J. Baker, Nancy A. Beck, Ellen L. Berg, et al. Advancing nonclinical innovation and safety in pharmaceutical testing. Drug Discovery Today. 2019;24(2):624-628. doi:10.1016/j.drudis.2018.11.011
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Kathrin Herrmann, Francesca Pistollato, Martin L. Stephens. Beyond the 3Rs: Expanding the use of human-relevant replacement methods in biomedical research. Alternatives to Animal Experimentation. 2019;36(3):343-352. doi:10.14573/altex.1907031
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Aroon D. Hingorani, Valerie Kuan, Chris Finan, et al. Improving the odds of drug development success through human genomics: modelling study. Scientific Reports. 2019;9(1):18911. doi:10.1038/s41598-019-54849-w
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Lucy Meigs, Lena Smirnova, Costanza Rovida, Marcel Leist, Thomas Hartung. Animal testing and its alternatives - the most important omics is economics. Alternatives to Animal Experimentation. 2018;35(3):275-305. doi:10.14573/altex.1807041
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A. Jain, R. Barrile, A. D. van der Meer, et al. Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics. Clinical Pharmacology and Therapeutics. 2018;103(2):332-340. doi:10.1002/cpt.742
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Shurong Hou, Hervé Tiriac, Banu Priya Sridharan, et al. Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening. SLAS discovery: advancing life sciences R & D. 2018;23(6):574-584. doi:10.1177/2472555218766842
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