Humans

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Decio L. Eizirik, Priscila L. Zimath. Diabetes research enters the biobank era: searching for the truth in a deep well. The Journal of Clinical Investigation. 2025;135(23):e199728. doi:10.1172/JCI199728
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Jacintha Shenton, Imein Bousnina, Michael Oropallo, et al. Opportunities and insights from pharmaceutical companies on the current use of new approach methodologies in nonclinical safety assessment. Drug Discovery Today. 2025;30(4):104328. doi:10.1016/j.drudis.2025.104328
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Alexandra Maertens, Thomas Luechtefeld, Jean Knight, Thomas Hartung. Alternative methods go green! Green toxicology as a sustainable approach for assessing chemical safety and designing safer chemicals. ALTEX. 2024;41(1):3-19. doi:10.14573/altex.2312291
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Raphaël Jeger-Madiot, Delphine Planas, Isabelle Staropoli, et al. Modeling memory B cell responses in a lymphoid organ-chip to evaluate mRNA vaccine boosting. The Journal of Experimental Medicine. 2024;221(10):e20240289. doi:10.1084/jem.20240289
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Inês Falcão-Pires. Alternatives to animal experimentation in cardiovascular research: human models of disease and biobanking. European Heart Journal. 2024;45(5):324-327. doi:10.1093/eurheartj/ehad709
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Li Pang, Chengzhong Cai, Praful Aggarwal, et al. Predicting oncology drug-induced cardiotoxicity with donor-specific iPSC-CMs-a proof-of-concept study with doxorubicin. Toxicological Sciences: An Official Journal of the Society of Toxicology. 2024;200(1):79-94. doi:10.1093/toxsci/kfae041
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Suel-Kee Kim, Seungmae Seo, Genevieve Stein-O’Brien, et al. Individual variation in the emergence of anterior-to-posterior neural fates from human pluripotent stem cells. Stem Cell Reports. 2024;19(9):1336-1350. doi:10.1016/j.stemcr.2024.07.004
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Noelia Antón-Bolaños, Irene Faravelli, Tyler Faits, et al. Brain Chimeroids reveal individual susceptibility to neurotoxic triggers. Nature. 2024;631(8019):142-149. doi:10.1038/s41586-024-07578-8
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Feline W. Lindhout, Fenna M. Krienen, Katherine S. Pollard, Madeline A. Lancaster. A molecular and cellular perspective on human brain evolution and tempo. Nature. 2024;630(8017):596-608. doi:10.1038/s41586-024-07521-x
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David Pamies, Jason Ekert, Marie-Gabrielle Zurich, et al. Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility. Stem Cell Reports. 2024;19(5):604-617. doi:10.1016/j.stemcr.2024.03.009
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