Drug Approval

Katerina Trajanoska, Claude Bhérer, Daniel Taliun, Sirui Zhou, J. Brent Richards, Vincent Mooser. From target discovery to clinical drug development with human genetics. Nature. 2023;620(7975):737-745. doi:10.1038/s41586-023-06388-8

Yuling Han, Xiaohua Duan, Liuliu Yang, et al. Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. Nature. 2021;589(7841):270-275. doi:10.1038/s41586-020-2901-9

Gail A. Van Norman. Drugs, Devices, and the FDA: Part 1: An Overview of Approval Processes for Drugs. JACC: Basic to Translational Science. 2016;1(3):170-179. doi:10.1016/j.jacbts.2016.03.002

Matthew R. Nelson, Hannah Tipney, Jeffery L. Painter, et al. The support of human genetic evidence for approved drug indications. Nature Genetics. 2015;47(8):856-860. doi:10.1038/ng.3314