disease modeling

Maedeh Mozneb, Madelyn Arzt, Jemima Moses, Sean Escopete, Lauren Wiegand, Arun Sharma. Stem cell research in space: Advancing regenerative medicine beyond Earth. Cell Stem Cell. 2025;32(10):1491-1508. doi:10.1016/j.stem.2025.09.001

Colin O’Hern, Sammantha Caywood, Shakhlo Aminova, et al. Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling. Cell Stem Cell. 2025;32(11):1671-1690.e13. doi:10.1016/j.stem.2025.09.011

Yi Liu, Rachna Balaji, Marcelo A. Szymanski de Toledo, et al. The pain target NaV1.7 is expressed late during human iPS cell differentiation into sensory neurons as determined in high-resolution imaging. Pflügers Archiv - European Journal of Physiology. 2024;476:975-992. doi:10.1007/s00424-024-02945-w

Sara Guerreiro, Patrícia Maciel. Transition from Animal-Based to Human Induced Pluripotent Stem Cells (iPSCs)-Based Models of Neurodevelopmental Disorders: Opportunities and Challenges. Cells. 2023;12(4):538. doi:10.3390/cells12040538

Julio Sempere, Suélen Andreia Rossi, Irene Chamorro-Herrero, et al. Minilungs from Human Embryonic Stem Cells to Study the Interaction of Streptococcus pneumoniae with the Respiratory Tract. Microbiology Spectrum. 2022;10(3):e0045322. doi:10.1128/spectrum.00453-22

Valeria V. Orlova, Dennis M. Nahon, Amy Cochrane, et al. Vascular defects associated with hereditary hemorrhagic telangiectasia revealed in patient-derived isogenic iPSCs in 3D vessels on chip. Stem Cell Reports. 2022;17(7):1536-1545. doi:10.1016/j.stemcr.2022.05.022

Xianwei Chen, Guoqiang Sun, E Tian, et al. Modeling Sporadic Alzheimer’s Disease in Human Brain Organoids under Serum Exposure. Advanced Science. 2021;8(18):2101462. doi:10.1002/advs.202101462

Ehsanollah Moradi, Sasan Jalili-Firoozinezhad, Mehran Solati-Hashjin. Microfluidic organ-on-a-chip models of human liver tissue. Acta Biomaterialia. 2020;116:67-83. doi:10.1016/j.actbio.2020.08.041

Kacey Ronaldson-Bouchard, Gordana Vunjak-Novakovic. Organs-on-a-Chip: A Fast Track for Engineered Human Tissues in Drug Development. Cell Stem Cell. 2018;22(3):310-324. doi:10.1016/j.stem.2018.02.011

Surjendu Maity, Tamanna Bhuyan, Christopher Jewell, et al. Recent Developments in Glioblastoma-On-A-Chip for Advanced Drug Screening Applications. Small. n/a(n/a):2405511. doi:10.1002/smll.202405511