Computational models

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Runxin Wu, Guinevere Ferreira, Nusrat Sadia Khan, et al. Digital twins and digital models of the human circulatory system. Nature Reviews Bioengineering. 2026;4(7):594-613. doi:10.1038/s44222-026-00427-5
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Sanan Venkatesh, Roman Kosoy, Zhenyi Wu, et al. Single-nucleus transcriptome-wide association study of human brain disorders. Nature. 2026;657(8133):1016-1026. doi:10.1038/s41586-026-10836-6
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Francesca Pistollato, Fabia Furtmann, Lindsay J. Marshall, et al. Advancing the frontier of rare disease modeling: a critical appraisal of in silico technologies. npj Digital Medicine. 2025;8(1):676. doi:10.1038/s41746-025-02068-1
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Frederic O. Dehnbostel, Vaibhav A. Dixit, Robert Preissner, Priyanka Banerjee. Non-animal models for blood–brain barrier permeability evaluation of drug-like compounds. Scientific Reports. 2024;14(1):8908. doi:10.1038/s41598-024-59734-9
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Nadav Yayon, Veronika R. Kedlian, Lena Boehme, et al. A spatial human thymus cell atlas mapped to a continuous tissue axis. Nature. 2024;635(8039):708-718. doi:10.1038/s41586-024-07944-6
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