Computational biology and bioinformatics

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Davide Ortolan, Pushkar Sathe, Andrei Volkov, et al. AI driven 3D subcellular RPE map discovers cell state transitions in establishment of apical-basal polarity. npj Artificial Intelligence. 2026;2(1):20. doi:10.1038/s44387-026-00074-6
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Rashmi Pandey, Jennifer Lee, Anahita Mojiri, John P. Cooke, Abhishek Jain. Time and architecture: the next two dimensions of microphysiological systems. npj Biomedical Innovations. 2026;3(1):22. doi:10.1038/s44385-026-00077-7
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Franziska J. Schöb, Alexander Binder, Valentina Zamarian, et al. Deep learning for predicting stem cell efficiency for use in beta cell differentiation. Scientific Reports. 2026. doi:10.1038/s41598-026-42830-3
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Ashley L. Eadie, Holly Fernandez Lynch, Naomi Scheinerman, Ravi B. Parikh. Advancing FDA New Approach Methodologies from animal models through digital twins. npj Digital Medicine. 2026. doi:10.1038/s41746-026-02476-x
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Arti Ahluwalia, Babette Fletemeyer, Giuseppe Chirico, et al. What’s in a NAM? Lab Animal. 2026:1-6. doi:10.1038/s41684-026-01731-8
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Chenfeng He, Athan Z. Li, Kalpana Hanthanan Arachchilage, et al. AI-based characterization of Alzheimer’s disease phenotypes from population-scale single-cell data. Nature Medicine. 2026:1-13. doi:10.1038/s41591-025-04128-1
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Pramod Bharadwaj Chandrashekar, Sayali Anil Alatkar, Noah Cohen Kalafut, et al. Personalized single-cell transcriptomics reveals molecular diversity in Alzheimer’s disease. Nature Communications. 2026;17(1):9596. doi:10.1038/s41467-026-72310-1
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Thomas Hartung, Maurice Whelan, Weida Tong, Robert M. Califf. Is regulatory science ready for artificial intelligence? npj Digital Medicine. 2025;8(1):1-5. doi:10.1038/s41746-025-01596-0
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Alexander G. Bury, Alicja Olejnik, Chiara Tocco, et al. Investigating the ageing-Parkinson’s disease nexus: standardisation of in vitro models and techniques by the PD-AGE network. npj Parkinson’s Disease. 2025;11(1):289. doi:10.1038/s41531-025-01137-2
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Sam N. Barnett, Ana-Maria Cujba, Lu Yang, et al. An organotypic atlas of human vascular cells. Nature Medicine. 2024:1-1. doi:10.1038/s41591-024-03376-x
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