Blood–brain barrier

Judit González-Gallego, Katalin Todorov-Völgyi, Stephan A. Müller, et al. A fully iPS-cell-derived 3D model of the human blood–brain barrier for exploring neurovascular disease mechanisms and therapeutic interventions. Nature Neuroscience. 2025:1-14. doi:10.1038/s41593-025-02123-w

Boning Qiu, Sara Pompe, Katerina T. Xenaki, et al. Generation of a perfusable three-dimensional human neurovascular chip to model brain drug delivery and immune cell extravasation. Journal of Controlled Release. 2025;387:114257. doi:10.1016/j.jconrel.2025.114257

Nienke R. Wevers, Arya Lekshmi Nair, Tania M. Fowke, et al. Modeling ischemic stroke in a triculture neurovascular unit on-a-chip. Fluids and Barriers of the CNS. 2021;18:59. doi:10.1186/s12987-021-00294-9

Goodwell Nzou, Robert T. Wicks, Nicole R. VanOstrand, et al. Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction. Scientific Reports. 2020;10:9766. doi:10.1038/s41598-020-66487-8