Biotechnology

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Sathish Selvam, Roberta S. Dos Reis, Marc C. E. Wagner, et al. Vascularized human brain organoids as a model of the brain–peripheral axis in HIV-1 neuropathogenesis. Scientific Reports. 2026. doi:10.1038/s41598-025-33940-5
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Jerome Lacombe, Sean E. Dunn, Marie Layac, et al. A human 3D culture-organ-on-chip platform for investigating the tumor microenvironment response to ionizing radiation. iScience. 2026;29(1). doi:10.1016/j.isci.2025.114236
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Dohui Kim, Jaeseung Youn, Juhyeok Kim, Jeongmin Lee, Jangwon Yoon, Dong Sung Kim. From organoid culture to manufacturing: technologies for reproducible and scalable organoid production. npj Biomedical Innovations. 2026;3(1):12. doi:10.1038/s44385-025-00054-6
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Andrew S. Robertson, Nahid Latif, Imein Bousnina, et al. Accelerating adoption of new approach methodologies in regulatory decision making: an industry perspective. Nature Reviews Drug Discovery. 2025. doi:10.1038/d41573-025-00038-6
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Andrea C. del Valle. Organs on chips could make biomedical research more equitable. Nature. 2025;644(8076):338-338. doi:10.1038/d41586-025-02569-9
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Andrew S. Robertson, Nahid Latif, Imein Bousnina, et al. Accelerating adoption of new approach methodologies in regulatory decision making: an industry perspective. Nature Reviews Drug Discovery. 2025;24(6):401-402. doi:10.1038/d41573-025-00038-6
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Jonas Jäger, Maria Thon, Katharina Schimek, Uwe Marx, Susan Gibbs, Jasper J. Koning. Differential biomarker expression of blood and lymphatic vasculature in multi-organ-chips. Scientific Reports. 2025;15(1):14492. doi:10.1038/s41598-025-96367-y
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Wim B. M. de Lau, Joost J. A. P. M. Wijnakker, Gijs J. F. van Son, et al. A single-chain derivative of an integrin-activating antibody potentiates organoid growth in Matrigel and collagen hydrogels. Nature Biotechnology. 2025:1-11. doi:10.1038/s41587-025-02874-8
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Khashayar Moshksayan, Rishika Khanna, Berk Camli, et al. A microfluidic platform for culturing and high-content imaging of adult stem cell-derived organoids. Scientific Reports. 2025;15(1):40162. doi:10.1038/s41598-025-23883-2
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Amy Hinterberger, Sara Bea. How do scientists model humanness? A qualitative study of human organoids in biomedical research. Social Science & Medicine. 2023;320:115676. doi:10.1016/j.socscimed.2023.115676
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