Kazuo Takayama

Chunhui Tian, Zheng Ao, Jonas Cerneckis, et al. Understanding monocyte-driven neuroinflammation in Alzheimer’s disease using human cortical organoid microphysiological systems. Science Advances. 2025;11(34):eadu2708. doi:10.1126/sciadv.adu2708

Sayaka Deguchi, Kaori Kosugi, Naoki Takeishi, et al. Construction of multilayered small intestine-like tissue by reproducing interstitial flow. Cell Stem Cell. 2024;31(9):1315-1326.e8. doi:10.1016/j.stem.2024.06.012

Sayaka Deguchi, Kaori Kosugi, Rina Hashimoto, et al. Elucidation of the liver pathophysiology of COVID-19 patients using liver-on-a-chips. PNAS Nexus. 2023;2(3):pgad029. doi:10.1093/pnasnexus/pgad029

Fuki Yokoi, Sayaka Deguchi, Kazuo Takayama. Organ-on-a-chip models for elucidating the cellular biology of infectious diseases. Biochimica Et Biophysica Acta. Molecular Cell Research. 2023;1870(6):119504. doi:10.1016/j.bbamcr.2023.119504

Rina Hashimoto, Junya Takahashi, Keisuke Shirakura, et al. SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression. Science Advances. 2022;8(38):eabo6783. doi:10.1126/sciadv.abo6783

Emi Sano, Tatsuya Suzuki, Rina Hashimoto, et al. Cell response analysis in SARS-CoV-2 infected bronchial organoids. Communications Biology. 2022;5(1):1-9. doi:10.1038/s42003-022-03499-2