Translation and validation

Christian A. Unger, Marion C Hope, Ahmed K. Aladhami, Kandy T. Velázquez, Reilly T. Enos. How stable is your vivarium’s temperature? Fluctuations in vivarium temperature significantly impact metabolism and behavior impeding scientific reproducibility. Physiology & Behavior. 2023;258:114029. doi:10.1016/j.physbeh.2022.114029

Alessia Moruzzi, Tanvi Shroff, Silke Keller, Peter Loskill, Madalena Cipriano. Training the Next Generation of Researchers in the Organ-on-Chip Field. Education Sciences. 2023;13(2):144. doi:10.3390/educsci13020144

Elijah J. Petersen, John T. Elliott, John Gordon, et al. Technical framework for enabling high quality measurements in new approach methodologies (NAMs). Alternatives to Animal Experimentation. 2023;40(1):174-186. doi:10.14573/altex.2205081

Lindsay J. Marshall, Jarrod Bailey, Manuela Cassotta, Kathrin Herrmann, Francesca Pistollato. Poor Translatability of Biomedical Research Using Animals — A Narrative Review. Alternatives to Laboratory Animals. 2023;51(2):102-135. doi:10.1177/02611929231157756

Annalisa Gastaldello, Camilla Bernasconi, Ivana Campia, et al. Building Indicators to Assess the Impact of EU-Funded Research into Alzheimer’s Disease, Breast Cancer and Prostate Cancer. Luxembourg: Publications Office of the European Union; 2023. doi:10.2760/63620

Duxin Sun, Wei Gao, Hongxiang Hu, Simon Zhou. Why 90% of clinical drug development fails and how to improve it? Acta Pharmaceutica Sinica B. 2022;12(7):3049-3062. doi:10.1016/j.apsb.2022.02.002

Passley Hargrove-Grimes, Lucie A. Low, Danilo A. Tagle. Microphysiological Systems: Stakeholder Challenges to Adoption in Drug Development. Cells Tissues Organs. 2022;211(3):269-281. doi:10.1159/000517422

Jack W. Scannell, James Bosley, John A. Hickman, et al. Predictive validity in drug discovery: what it is, why it matters and how to improve it. Nature Reviews Drug Discovery. 2022;21(12):915-931. doi:10.1038/s41573-022-00552-x

Tracy D. Zhang, Scott C. Kolbe, Leah C. Beauchamp, Ella K. Woodbridge, David I. Finkelstein, Emma L. Burrows. How Well Do Rodent Models of Parkinson’s Disease Recapitulate Early Non-Motor Phenotypes? A Systematic Review. Biomedicines. 2022;10(12):3026. doi:10.3390/biomedicines10123026

Szczepan W. Baran, Paul C. Brown, Andreas R. Baudy, et al. Perspectives on the evaluation and adoption of complex in vitro models in drug development: Workshop with the FDA and the pharmaceutical industry (IQ MPS Affiliate). Alternatives to Animal Experimentation. 2022;39(2):297-314. doi:10.14573/altex.2112203