Translation and validation

1.
Xu Han, Kehan Ren, Pan Wang, et al. Spatial transcriptomic analyses highlight distinct erythroid niches in mice and humans. Nature Genetics. 2026:1-12. doi:10.1038/s41588-026-02671-2
View Full Reference
1.
Judith C. Madden, Steven J. Enoch, Alicia Paini, Mark T.D. Cronin. Redefining the gold standard and recommendations to accelerate the adoption of New Approach Methodologies (NAMs) in support of the Three Rs. Alternatives to Laboratory Animals. 2026;54(2):85-100. doi:10.1177/02611929261423850
View Full Reference
1.
Fernando Pardo-Manuel de Villena, James M. Amos-Landgraf, Timothy A. Bell, et al. Improve genetic quality control to increase rigor and reproducibility of mouse research. Science. 2026;392(6799):698-700. doi:10.1126/science.aec3177
View Full Reference
1.
Vaishali Sahasrabudhe, Timothy Nicholas, Gianluca Nucci, Cynthia J Musante, Brian Corrigan. Impact of Model-Informed Drug Development on Drug Development Cycle Times and Clinical Trial Cost. Clinical Pharmacology & Therapeutics. 2025;118(2):378-385. doi:10.1002/cpt.3636
View Full Reference
1.
Hamideh Frühwein, Norbert W. Paul. “Lost in translation?” Animal research in the era of precision medicine. Journal of Translational Medicine. 2025;23(1):152. doi:10.1186/s12967-025-06084-3
View Full Reference
1.
Sarah E. Wolfensohn, Vera Baumans, F. Josef van der Staay, Saskia S. Arndt. Implications of stress for animal welfare and animal-based research†. Laboratory Animals. 2025:00236772251396310. doi:10.1177/00236772251396310
View Full Reference
1.
Alexis R. Katz, Margaret P. Huntwork, Jay K. Kolls, et al. Impact of psychological stressors on natural killer cell function: A comprehensive analysis based on stressor type, duration, intensity, and species. Physiology & Behavior. 2025;288:114734. doi:10.1016/j.physbeh.2024.114734
View Full Reference
1.
Lindsay J. Marshall, Kathleen M. Conlee. The case of the missing mouse—developing cystic fibrosis drugs without using animals. Frontiers in Drug Discovery. 2024;4. doi:10.3389/fddsv.2024.1347246
View Full Reference
1.
Ingrid Berg, Pia Härvelid, Wolfgang Emanuel Zürrer, Marianna Rosso, Daniel S. Reich, Benjamin Victor Ineichen. Which experimental factors govern successful animal-to-human translation in multiple sclerosis drug development? A systematic review and meta-analysis. eBioMedicine. 2024;110. doi:10.1016/j.ebiom.2024.105434
View Full Reference
1.
Ana Ubago-Rodríguez, María I. Quiñones-Vico, Manuel Sánchez-Díaz, et al. Challenges in Psoriasis Research: A Systematic Review of Preclinical Models. Dermatology. 2024;240(4):620-652. doi:10.1159/000538993
View Full Reference