Reviews and perspectives

Marit Keuper-Navis, Markus Walles, Birk Poller, et al. The application of organ-on-chip models for the prediction of human pharmacokinetic profiles during drug development. Pharmacological Research. 2023;195:106853. doi:10.1016/j.phrs.2023.106853

Daniel Levner, Lorna Ewart. Integrating Liver-Chip data into pharmaceutical decision-making processes. Expert Opinion on Drug Discovery. 2023;18(12):1313-1320. doi:10.1080/17460441.2023.2255127

Emily Golden, David Allen, Alexander Amberg, et al. Toward implementing virtual control groups in nonclinical safety studies: Workshop report and roadmap to implementation. ALTEX - Alternatives to animal experimentation. 2023. doi:10.14573/altex.2310041

Giuseppe Calà, Beatrice Sina, Paolo De Coppi, Giovanni Giuseppe Giobbe, Mattia Francesco Maria Gerli. Primary human organoids models: Current progress and key milestones. Frontiers in Bioengineering and Biotechnology. 2023;11. https://www.frontiersin.org/articles/10.3389/fbioe.2023.1058970.

Kim Bak Jensen, Melissa Helen Little. Organoids are not organs: Sources of variation and misinformation in organoid biology. Stem Cell Reports. 2023;18(6):1255-1270. doi:10.1016/j.stemcr.2023.05.009

Humira Assad, Arvina Assad, Ashish Kumar. Recent Developments in 3D Bio-Printing and Its Biomedical Applications. Pharmaceutics. 2023;15(1):255. doi:10.3390/pharmaceutics15010255

David M. Stresser, Anna K. Kopec, Philip Hewitt, et al. Towards in vitro models for reducing or replacing the use of animals in drug testing. Nature Biomedical Engineering. 2023:1-6. doi:10.1038/s41551-023-01154-7

Amid Shakeri, Ying Wang, Yimu Zhao, et al. Engineering Organ-on-a-Chip Systems for Vascular Diseases. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023;43(12):2241-2255. doi:10.1161/ATVBAHA.123.318233

LV Shiya, Enhui He, Jinping Luo, et al. Using Human-Induced Pluripotent Stem Cell Derived Neurons on Microelectrode Arrays to Model Neurological Disease: A Review. Advanced Science. 2023;10(33):2301828. doi:10.1002/advs.202301828

Anna Loewa, James J. Feng, Sarah Hedtrich. Human disease models in drug development. Nature Reviews Bioengineering. 2023;1(8):545-559. doi:10.1038/s44222-023-00063-3