Renal/urinary system

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Emma Warrner, Aria Zheyuan Huang, Alex J. Hughes. Developmentally inspired synthetic kidney engineering. Nature Biotechnology. 2026:1-14. doi:10.1038/s41587-026-03011-9
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Gabriele Addario, Chiara Formica, Lorenzo Moroni, Carlos Mota. 3D printed chip as platform to vascularize hiPSCs-derived kidney organoids. Biomedical Microdevices. 2026;28(2):49. doi:10.1007/s10544-026-00829-7
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Connor C. Fausto, Fokion Glykofrydis, Navneet Kumar, et al. Patterning human kidney organoids with synthetic Wnt-secreting organizers. Science. 2026;393(6806):eadu9122. doi:10.1126/science.adu9122
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Beatrice Gabbin, James Gallant, Fangchen Liu, et al. In vitro modeling of renal injury-induced cardiac effects using human iPSC-derived organoids. Cell Communication and Signaling. 2026;24(1):380. doi:10.1186/s12964-026-02902-3
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Ramila E. Gulieva, Parvaneh Ahmadvand, Benjamin S. Freedman. A novel rapalog shows improved safety vs. efficacy in a human organoid model of polycystic kidney disease. Stem Cell Reports. 2025;20(2). doi:10.1016/j.stemcr.2024.102395
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William J. Mason, Jennifer C. Chandler, Alice M. Gage, et al. Vincristine Treatment Protects Against Podocyte Damage in Focal Segmental Glomerulosclerosis. Kidney International Reports. 2025. doi:10.1016/j.ekir.2025.08.002
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Oscar J. Abilez, Huaxiao Yang, Yuan Guan, et al. Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization. Science. 2025;388(6751):eadu9375. doi:10.1126/science.adu9375
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Moritz Lassé, Jamal El Saghir, Celine C. Berthier, et al. An integrated organoid omics map extends modeling potential of kidney disease. Nature Communications. 2023;14(1):4903. doi:10.1038/s41467-023-39740-7
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Blue B. Lake, Rajasree Menon, Seth Winfree, et al. An atlas of healthy and injured cell states and niches in the human kidney. Nature. 2023;619(7970):585-594. doi:10.1038/s41586-023-05769-3
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Vivian V. T. Nguyen, Vasiliki Gkouzioti, Christian Maass, Marianne C. Verhaar, Robin W. M. Vernooij, Bas W. M. van Balkom. A systematic review of kidney-on-a-chip-based models to study human renal (patho-)physiology. Disease Models & Mechanisms. 2023;16(6):dmm050113. doi:10.1242/dmm.050113
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