Nervous system

Bilal Cakir, Yoshiaki Tanaka, Ferdi Ridvan Kiral, et al. Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids. Nature Communications. 2022;13(1):430. doi:10.1038/s41467-022-28043-y

Florencia D. Haase, Bronte Coorey, Lisa Riley, Laurence C. Cantrill, Patrick P. L. Tam, Wendy A. Gold. Pre-clinical Investigation of Rett Syndrome Using Human Stem Cell-Based Disease Models. Frontiers in Neuroscience. 2021;15. https://www.frontiersin.org/articles/10.3389/fnins.2021.698812.

Zhonglin Lyu, Jon Park, Kwang-Min Kim, et al. A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke. Nature Biomedical Engineering. 2021;5(8):847-863. doi:10.1038/s41551-021-00744-7

Foluwasomi A. Oyefeso, Alysson R. Muotri, Christopher G. Wilson, Michael J. Pecaut. Brain organoids: A promising model to assess oxidative stress-induced central nervous system damage. Developmental Neurobiology. 2021;81(5):653-670. doi:10.1002/dneu.22828

Jonas Simon Fleck, Fátima Sanchís-Calleja, Zhisong He, et al. Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases. Cell Stem Cell. 2021;28(6):1177-1180. doi:10.1016/j.stem.2021.03.015

Nienke R. Wevers, Arya Lekshmi Nair, Tania M. Fowke, et al. Modeling ischemic stroke in a triculture neurovascular unit on-a-chip. Fluids and Barriers of the CNS. 2021;18:59. doi:10.1186/s12987-021-00294-9

Katarina Stoklund Dittlau, Emily N. Krasnow, Laura Fumagalli, et al. Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition. Stem Cell Reports. 2021;16(9):2213-2227. doi:10.1016/j.stemcr.2021.03.029

Cameron S. Cowan, Magdalena Renner, Martina De Gennaro, et al. Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution. Cell. 2020;182(6):1623-1640.e34. doi:10.1016/j.cell.2020.08.013

Goodwell Nzou, Robert T. Wicks, Nicole R. VanOstrand, et al. Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction. Scientific Reports. 2020;10:9766. doi:10.1038/s41598-020-66487-8

Kyla Nichols, Ryan Koppes, Abigail Koppes. Recent advancements in microphysiological systems for neural development and disease. Current Opinion in Biomedical Engineering. 2020;14:42-51. doi:10.1016/j.cobme.2020.05.003