Nervous system

Chiara Barberio, Aimee Withers, Yash Mishra, et al. A human-derived neurovascular unit in vitro model to study the effects of cellular cross-talk and soluble factors on barrier integrity. Frontiers in Cellular Neuroscience. 2022;16:1065193. doi:10.3389/fncel.2022.1065193

Iosif Pediaditakis, Konstantia R. Kodella, Dimitris V. Manatakis, et al. A microengineered Brain-Chip to model neuroinflammation in humans. iScience. 2022;25(8):104813. doi:10.1016/j.isci.2022.104813

Kevin W. Kelley, Sergiu P. Pașca. Human brain organogenesis: Toward a cellular understanding of development and disease. Cell. 2022;185(1):42-61. doi:10.1016/j.cell.2021.10.003

Oliver L. Eichmüller, Juergen A. Knoblich. Human cerebral organoids - a new tool for clinical neurology research. Nature Reviews. Neurology. 2022;18(11):661-680. doi:10.1038/s41582-022-00723-9

Louise Miny, Benoît G. C. Maisonneuve, Isabelle Quadrio, Thibault Honegger. Modeling Neurodegenerative Diseases Using In Vitro Compartmentalized Microfluidic Devices. Frontiers in Bioengineering and Biotechnology. 2022;10:919646. doi:10.3389/fbioe.2022.919646

Manuela Cassotta, Hugo Geerts, Lise Harbom, et al. The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible. ALTEX. 2022;39(4):694-709. doi:10.14573/altex.2203161

Carolyn P. Neuhaus. Threats to Benefits: Assessing Knowledge Production in Nonhuman Models of Human Neuropsychiatric Disorders. The Hastings Center Report. 2022;52 Suppl 2(Suppl 2):S34-S40. doi:10.1002/hast.1430

Joseph J. Y. Wong, Balazs V. Varga, Ragnhildur Thóra Káradóttir, Elizabeth A. H. Hall. Electrochemically induced in vitro focal hypoxia in human neurons. Frontiers in Cell and Developmental Biology. 2022;10. doi:10.3389/fcell.2022.968341

Florencia D. Haase, Bronte Coorey, Lisa Riley, Laurence C. Cantrill, Patrick P. L. Tam, Wendy A. Gold. Pre-clinical Investigation of Rett Syndrome Using Human Stem Cell-Based Disease Models. Frontiers in Neuroscience. 2021;15. https://www.frontiersin.org/articles/10.3389/fnins.2021.698812.

Zhonglin Lyu, Jon Park, Kwang-Min Kim, et al. A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke. Nature Biomedical Engineering. 2021;5(8):847-863. doi:10.1038/s41551-021-00744-7