Liver

Zhichao Ye, Jianing Yan, Yuheng Wang, et al. Three-dimensional bioprinted hiHeps hepatorganoids with enhanced hepatic functions for the treatment of liver failure and promotion of liver regeneration. Bioactive Materials. 2026;58:550-573. doi:10.1016/j.bioactmat.2025.12.024

Iris Marchal. Human periportal liver assembloids. Nature Biotechnology. 2026;44(1):39-39. doi:10.1038/s41587-025-02993-2

Milad Rezvani, Susanna Quach, Kyle Lewis, et al. Modeling immune lineage co-development in human pluripotent stem cell-derived liver organoids. Journal of Hepatology. 2025. doi:10.1016/j.jhep.2025.11.018

Hasan Al Reza, Connie Santangelo, Kentaro Iwasawa, et al. Multi-zonal liver organoids from human pluripotent stem cells. Nature. 2025:1-10. doi:10.1038/s41586-025-08850-1

Ryo Igarashi, Mayumi Oda, Ryo Okada, et al. Generation of human adult hepatocyte organoids with metabolic functions. Nature. 2025:1-10. doi:10.1038/s41586-025-08861-y

Wei Wu, Faiza Anas, Baran Koc, et al. Multi-organ model assessment of neurotoxicity following exposure of liver spheroids to drugs. Biomedicine & Pharmacotherapy. 2025;186:118021. doi:10.1016/j.biopha.2025.118021

Yuki Ueda, Satoshi Omiya, Jonathan Pinney, Michelle A. Bylicky, Molykutty J. Aryankalayil. Liver quad culture chip as a model for radiation injury research. Scientific Reports. 2025;15(1):12414. doi:10.1038/s41598-025-96140-1

Shuntaro Kawamura, Yosuke Yoneyama, Norikazu Saiki, et al. Modeling antithymocyte globulin-induced microvasculopathy using human iPSC-derived vascularized liver organoids. Cell Reports Medicine. 2025. doi:10.1016/j.xcrm.2025.102433

Ahmed S M Ali, Dongwei Wu, Viola Roehrs, et al. Liver-on-Micropillar: a humanized, animal-free platform for high-throughput assessment of drug-induced liver injury. Biofabrication. 2025;17(4):045022. doi:10.1088/1758-5090/ae1063

Elizabeth K. Johnston, Zhou Fang, Alejandro Soto-Gutierrez, et al. Engineering a three-dimensional liver steatosis model. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2025;1871(6):167888. doi:10.1016/j.bbadis.2025.167888