Immune/infectious disease

Gabriela S. Kronemberger, Fabiana A. Carneiro, Danielle F. Rezende, Leandra S. Baptista. Spheroids and organoids as humanized 3D scaffold-free engineered tissues for SARS-CoV-2 viral infection and drug screening. Artificial Organs. 2021;45(6):548-558. doi:10.1111/aor.13880

Yaqing Wang, Peng Wang, Jianhua Qin. Microfluidic Organs-on-a-Chip for Modeling Human Infectious Diseases. Accounts of Chemical Research. 2021;54(18):3550-3562. doi:10.1021/acs.accounts.1c00411

Jeonghwan Youk, Taewoo Kim, Kelly V. Evans, et al. Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2. Cell Stem Cell. 2020;27(6). doi:10.1016/j.stem.2020.10.004

Yotam E. Bar-Ephraim, Kai Kretzschmar, Hans Clevers. Organoids in immunological research. Nature Reviews. Immunology. 2020;20(5):279-293. doi:10.1038/s41577-019-0248-y

Ruochen Zang, Maria Florencia Gomez Castro, Broc T. McCune, et al. TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes. Science Immunology. 2020;5(47):eabc3582. doi:10.1126/sciimmunol.abc3582

Hiroaki Katsura, Vishwaraj Sontake, Aleksandra Tata, et al. Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction. Cell Stem Cell. 2020;27(6):890-904.e8. doi:10.1016/j.stem.2020.10.005

Zhongmin Tang, Na Kong, Xingcai Zhang, et al. A materials-science perspective on tackling COVID-19. Nature Reviews Materials. 2020;5(11):847-860. doi:10.1038/s41578-020-00247-y

Vanessa Monteil, Hyesoo Kwon, Patricia Prado, et al. Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2. Cell. 2020;181(4):905-913.e7. doi:10.1016/j.cell.2020.04.004

Holly Ryan, Chelsey S. Simmons. Potential Applications of Microfluidics to Acute Kidney Injury Associated with Viral Infection. Cellular and Molecular Bioengineering. 2020;13(4):305-311. doi:10.1007/s12195-020-00649-6

Huaqi Tang, Yasmine Abouleila, Longlong Si, et al. Human Organs-on-Chips for Virology. Trends in Microbiology. 2020;28(11):934-946. doi:10.1016/j.tim.2020.06.005