Immune/infectious disease

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Partho Protim Adhikary, Qurrat Ul Ain, Andreas Christian Hocke, Sarah Hedtrich. COVID-19 highlights the model dilemma in biomedical research. Nature Reviews Materials. 2021;6(5):374-376. doi:10.1038/s41578-021-00305-z
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Smriti Mallapaty. The mini lungs and other organoids helping to beat COVID. Nature. 2021;593(7860):492-494. doi:10.1038/d41586-021-01395-z
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A. L. Gard, R. J. Luu, C. R. Miller, et al. High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro. Scientific Reports. 2021;11(1):14961. doi:10.1038/s41598-021-94095-7
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Jelte van der Vaart, Mart M. Lamers, Bart L. Haagmans, Hans Clevers. Advancing lung organoids for COVID-19 research. Disease Models & Mechanisms. 2021;14(6):dmm049060. doi:10.1242/dmm.049060
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Alice Maria Giani, Shuibing Chen. Human pluripotent stem cell-based organoids and cell platforms for modelling SARS-CoV-2 infection and drug discovery. Stem Cell Research. 2021;53:102207. doi:10.1016/j.scr.2021.102207
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Mart M. Lamers, Tim I. Breugem, Anna Z. Mykytyn, et al. Human organoid systems reveal in vitro correlates of fitness for SARS-CoV-2 B.1.1.7. 2021:2021.05.03.441080. doi:10.1101/2021.05.03.441080
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Miriane de Oliveira, Maria T. De Sibio, Felipe A. S. Costa, Marna E. Sakalem. Airway and Alveoli Organoids as Valuable Research Tools in COVID-19. ACS Biomaterials Science & Engineering. 2021;7(8):3487-3502. doi:10.1021/acsbiomaterials.1c00306
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Bruna A. G. de Melo, Julia C. Benincasa, Elisa M. Cruz, Juliana Terzi Maricato, Marimelia A. Porcionatto. 3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to bioprinting. Biomedical Journal. 2021;44(1):31-42. doi:10.1016/j.bj.2020.11.009
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Vivek V. Thacker, Kunal Sharma, Neeraj Dhar, Gian-Filippo Mancini, Jessica Sordet-Dessimoz, John D. McKinney. Rapid endotheliitis and vascular damage characterize SARS-CoV-2 infection in a human lung-on-chip model. EMBO reports. 2021;22(6):e52744. doi:10.15252/embr.202152744
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Yuling Han, Xiaohua Duan, Liuliu Yang, et al. Identification of SARS-CoV-2 inhibitors using lung and colonic organoids. Nature. 2021;589(7841):270-275. doi:10.1038/s41586-020-2901-9
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