Immune/infectious disease

Nathalia Almeida, Sam Acors, Daniel Cox, et al. Generation and characterization of iPSC models from HIV-1-positive individuals with divergent clinical outcomes. Stem Cell Reports. 2026. doi:10.1016/j.stemcr.2025.102786

Pamela E. Capendale, Anoop T. Ambikan, Inés García-Rodríguez, et al. Parechovirus-3 infection disrupts immunometabolism and leads to glutamate excitotoxicity in neural organoids. Cellular and Molecular Life Sciences. 2025;82(1):382. doi:10.1007/s00018-025-05926-z

Rachel Ringquist, Eshant Bhatia, Paramita Chatterjee, et al. An immune-competent lung-on-a-chip for modelling the human severe influenza infection response. Nature Biomedical Engineering. 2025:1-23. doi:10.1038/s41551-025-01491-9

Andrew I. Morrison, Jonas Jäger, Charlotte M. de Winde, et al. Integration of lymphatic vasculature to a human lymph node-on-chip enhances physiological immune properties. Materials Today Bio. 2025;35:102326. doi:10.1016/j.mtbio.2025.102326

Jonas Jäger, Maria Thon, Katharina Schimek, Uwe Marx, Susan Gibbs, Jasper J. Koning. Differential biomarker expression of blood and lymphatic vasculature in multi-organ-chips. Scientific Reports. 2025;15(1):14492. doi:10.1038/s41598-025-96367-y

Anna Niarakis, Gary An, Luiz Ladeira, et al. Building Immune Digital Twins: An International and Transdisciplinary Community Effort. ImmunoInformatics. 2025. doi:10.1016/j.immuno.2025.100060

S. Tori Ellison, Ian Hayman, Kristy Derr, et al. Limitations of acyclovir and identification of potent HSV antivirals using 3D bioprinted human skin equivalents. Nature Communications. 2025;16(1):9200. doi:10.1038/s41467-025-64245-w

Yuncheng Man, Ryan R. Posey, Haiqing Bai, et al. Preclinical assessment of pan-influenza A virus CRISPR RNA therapeutics in a human lung alveolus chip. Lab on a Chip. 2025. doi:10.1039/D5LC00156K

Anubama Rajan, Divya Nagaraj, Carolyn Bomidi, et al. Single cell sequencing analysis of respiratory syncytial virus–infected pediatric and adult human nose organoids reveals age differences, proliferative diversity and identifies novel cellular tropism. Journal of Infection. 2025;91(4). doi:10.1016/j.jinf.2025.106617

Andrea I. Boyd, Leah A. Kafer, Isabel F. Escapa, et al. Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids. mSphere. 2025;10(10):e00493-25. doi:10.1128/msphere.00493-25