Endocrine system

Ninouk Akkerman, Quan Xu, Alberto Valdeolivas, et al. An organoid model of the human adrenal cortex identifies drivers of steroidogenesis and zonation. Cell Press Blue. 2026. doi:10.1016/j.cpblue.2026.100015

Michinori Mayama, Eoin C. Whelan, Takeshi Sato, et al. Modeling human prenatal adrenocortical functional zonation dynamics from pluripotent stem cells. Cell Stem Cell. 2026;33(3):454-469.e9. doi:10.1016/j.stem.2026.02.002

Decio L. Eizirik, Priscila L. Zimath. Diabetes research enters the biobank era: searching for the truth in a deep well. The Journal of Clinical Investigation. 2025;135(23):e199728. doi:10.1172/JCI199728

Katharina Schlünder, Madalena Cipriano, Aline Zbinden, et al. Microphysiological pancreas-on-chip platform with integrated sensors to model endocrine function and metabolism. Lab on a Chip. 2024. doi:10.1039/D3LC00838J

Lindsey K. Huff, Charles M. Amurgis, Lauren E. Kokai, Rosalyn D. Abbott. Optimization and validation of a fat-on-a-chip model for non-invasive therapeutic drug discovery. Frontiers in Bioengineering and Biotechnology. 2024;12. doi:10.3389/fbioe.2024.1404327

Katie Hamel, Emma Rogers, Jeffrey M. Gimble, Trivia Frazier, Cecilia Sanchez. Functional Assays in 3D ObaCell® Fat-on-a-Chip Cultures: Lipolysis and Glucose Uptake Assays. Methods in Molecular Biology (Clifton, N.J.). 2024;2783:323-333. doi:10.1007/978-1-0716-3762-3_23

Amanda Andersson-Rolf, Kelvin Groot, Jeroen Korving, et al. Long-term in vitro expansion of a human fetal pancreas stem cell that generates all three pancreatic cell lineages. Cell. 2024. doi:10.1016/j.cell.2024.10.044

Alessandro Cherubini, Francesco Rusconi, Roberta Piras, et al. Exploring human pancreatic organoid modelling through single-cell RNA sequencing analysis. Communications Biology. 2024;7(1):1-16. doi:10.1038/s42003-024-07193-3

Belin Selcen Beydag-Tasöz, Siham Yennek, Anne Grapin-Botton. Towards a better understanding of diabetes mellitus using organoid models. Nature Reviews Endocrinology. 2023;19(4):232-248. doi:10.1038/s41574-022-00797-x

Tingting Tao, Pengwei Deng, Yaqing Wang, et al. Microengineered Multi-Organoid System from hiPSCs to Recapitulate Human Liver-Islet Axis in Normal and Type 2 Diabetes. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 2022;9(5):e2103495. doi:10.1002/advs.202103495