Cardiovascular system

Huub J. Weener, Heleen H. T. Middelkamp, Andries D. van der Meer. Considering future qualification for regulatory science in the early development of microphysiological systems: a case study of microthrombosis in a Vessel-on-Chip. Frontiers in Toxicology. 2024;6. doi:10.3389/ftox.2024.1513002

Ulgu Arslan, Marcella Brescia, Viviana Meraviglia, et al. Vascularized hiPSC-derived 3D cardiac microtissue on chip. Stem Cell Reports. 2023;18(7):1394-1404. doi:10.1016/j.stemcr.2023.06.001

Brett Volmert, Artem Kiselev, Aniwat Juhong, et al. A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization. Nature Communications. 2023;14:8245. doi:10.1038/s41467-023-43999-1

Tiannan Liu, Enno Klussmann. Targeting cAMP signaling compartments in iPSC-derived models of cardiovascular disease. Current Opinion in Pharmacology. 2023;71:102392. doi:10.1016/j.coph.2023.102392

Omar Mourad, Ryan Yee, Mengyuan Li, Sara S. Nunes. Modeling Heart Diseases on a Chip: Advantages and Future Opportunities. Circulation Research. 2023;132(4):483-497. doi:10.1161/CIRCRESAHA.122.321670

Justin Silberman, Jessica Boehlein, Talia Abbate, Erika Moore. A Biomaterial Model to Assess the Effects of Age in Vascularization. Cells Tissues Organs. 2023;212(1):74-83. doi:10.1159/000523859

Yuhao Qiang, Abdoulaye Sissoko, Zixiang L. Liu, et al. Microfluidic study of retention and elimination of abnormal red blood cells by human spleen with implications for sickle cell disease. Proceedings of the National Academy of Sciences. 2023;120(6):e2217607120. doi:10.1073/pnas.2217607120

Roberta Visone, Ferran Lozano-Juan, Simona Marzorati, et al. Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform. Toxicological Sciences. 2023;191(1):47-60. doi:10.1093/toxsci/kfac108

Kirill Salewskij, Josef M. Penninger. Blood Vessel Organoids for Development and Disease. Circulation Research. 2023;132(4):498-510. doi:10.1161/CIRCRESAHA.122.321768

Yumiko Sakurai, Elaissa T. Hardy, Wilbur A. Lam. Hemostasis-on-a-chip / incorporating the endothelium in microfluidic models of bleeding. Platelets. 2023;34(1):2185453. doi:10.1080/09537104.2023.2185453