Cancer

Johannes Dornhof, Jochen Kieninger, Harshini Muralidharan, Jochen Maurer, Gerald A. Urban, Andreas Weltin. Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures. Lab on a Chip. 2022;22(2):225-239. doi:10.1039/D1LC00689D

Gabrielle Wishart, Priyanka Gupta, Andrew Nisbet, Giuseppe Schettino, Eirini Velliou. On the Evaluation of a Novel Hypoxic 3D Pancreatic Cancer Model as a Tool for Radiotherapy Treatment Screening. Cancers. 2021;13(23):6080. doi:10.3390/cancers13236080

Amanda M. Clark, Nancy L. Allbritton, Alan Wells. Integrative microphysiological tissue systems of cancer metastasis to the liver. Seminars in Cancer Biology. 2021;71:157-169. doi:10.1016/j.semcancer.2020.06.010

Jennifer M. Rosenbluth, Ron C. J. Schackmann, G. Kenneth Gray, et al. Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages. Nature Communications. 2020;11(1):1711. doi:10.1038/s41467-020-15548-7

Else Driehuis, Kai Kretzschmar, Hans Clevers. Establishment of patient-derived cancer organoids for drug-screening applications. Nature Protocols. 2020;15(10):3380-3409. doi:10.1038/s41596-020-0379-4

Kanako Yuki, Ning Cheng, Michitaka Nakano, Calvin J. Kuo. Organoid Models of Tumor Immunology. Trends in Immunology. 2020;41(8):652-664. doi:10.1016/j.it.2020.06.010

David Tuveson, Hans Clevers. Cancer modeling meets human organoid technology. Science (New York, N.Y.). 2019;364(6444):952-955. doi:10.1126/science.aaw6985

Jarno Drost, Hans Clevers. Organoids in cancer research. Nature Reviews. Cancer. 2018;18(7):407-418. doi:10.1038/s41568-018-0007-6

Shurong Hou, Hervé Tiriac, Banu Priya Sridharan, et al. Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening. SLAS discovery: advancing life sciences R & D. 2018;23(6):574-584. doi:10.1177/2472555218766842

Norman Sachs, Joep de Ligt, Oded Kopper, et al. A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity. Cell. 2018;172(1-2):373-386.e10. doi:10.1016/j.cell.2017.11.010