Aging

Jonas Cerneckis, Guojun Bu, Yanhong Shi. Pushing the boundaries of brain organoids to study Alzheimer’s disease. Trends in Molecular Medicine. 2023;29(8):659-672. doi:10.1016/j.molmed.2023.05.007

Francesca Veronesi, Deyanira Contartese, Laura Di Sarno, Veronica Borsari, Milena Fini, Gianluca Giavaresi. In Vitro Models of Cell Senescence: A Systematic Review on Musculoskeletal Tissues and Cells. International Journal of Molecular Sciences. 2023;24(21):15617. doi:10.3390/ijms242115617

Christiane Hartmann, Luise Herling, Alexander Hartmann, et al. Systematic estimation of biological age of in vitro cell culture systems by an age-associated marker panel. Frontiers in Aging. 2023;4. doi:10.3389/fragi.2023.1129107

Eunkyung Clare Ko, Sarah Spitz, Francesca Michela Pramotton, et al. Accelerating the in vitro emulation of Alzheimer’s disease-associated phenotypes using a novel 3D blood-brain barrier neurosphere co-culture model. Frontiers in Bioengineering and Biotechnology. 2023;11. doi:10.3389/fbioe.2023.1251195

C. Kwon Kim, Yin Rui Lee, Lynnett Ong, Michael Gold, Amir Kalali, Joydeep Sarkar. Alzheimer’s Disease: Key Insights from Two Decades of Clinical Trial Failures. Journal of Alzheimer’s Disease. 2022;87(1):83-100. doi:10.3233/JAD-215699

Xianwei Chen, Guoqiang Sun, E Tian, et al. Modeling Sporadic Alzheimer’s Disease in Human Brain Organoids under Serum Exposure. Advanced Science. 2021;8(18):2101462. doi:10.1002/advs.202101462

Mihyeon Bae, Hee-Gyeong Yi, Jinah Jang, Dong-Woo Cho. Microphysiological Systems for Neurodegenerative Diseases in Central Nervous System. Micromachines. 2020;11(9):855. doi:10.3390/mi11090855

Yan Li, Danni Li, Pei Zhao, Krishnaswamy Nandakumar, Liqiu Wang, Youqiang Song. Microfluidics-Based Systems in Diagnosis of Alzheimer’s Disease and Biomimetic Modeling. Micromachines. 2020;11(9):787. doi:10.3390/mi11090787

Jennifer L. Hu, Michael E. Todhunter, Mark A. LaBarge, Zev J. Gartner. Opportunities for organoids as new models of aging. Journal of Cell Biology. 2017;217(1):39-50. doi:10.1083/jcb.201709054

Morgan Dos Santos, Elodie Metral, Aurélie Boher, Patricia Rousselle, Amélie Thepot, Odile Damour. In vitro 3-D model based on extending time of culture for studying chronological epidermis aging. Matrix Biology. 2015;47:85-97. doi:10.1016/j.matbio.2015.03.009