Translation and validation

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Mathias Busek, Aleksandra Aizenshtadt, Mikel Amirola-Martinez, Ludivine Delon, Stefan Krauss. Academic User View: Organ-on-a-Chip Technology. Biosensors. 2022;12(2):126. doi:10.3390/bios12020126
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Biotechnology Innovation Organization, Informa Pharma Intelligence, Quantitative Life Sciences. Clinical Development Success Rates and Contributing Factors 2011-2020.; 2021:34. https://go.bio.org/rs/490-EHZ-999/images/ClinicalDevelopmentSuccessRates2011_2020.pdf.
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Hubert Dirven, Gunn E. Vist, Sricharan Bandhakavi, et al. Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review. Scientific Reports. 2021;11(1):6403. doi:10.1038/s41598-021-85708-2
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Michael Balls. It’s Time to Include Harm to Humans in Harm–Benefit Analysis — But How to Do It, That is the Question. Alternatives to Laboratory Animals. 2021;49(5):182-196. doi:10.1177/02611929211062223
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Désirée H. Veening-Griffioen, Guilherme S. Ferreira, Wouter P. C. Boon, et al. Tradition, not science, is the basis of animal model selection in translational and applied research. ALTEX. 2021;38(1):49-62. doi:10.14573/altex.2003301
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Simon Lohse. Scientific inertia in animal-based research in biomedicine. Studies in History and Philosophy of Science Part A. 2021;89:41-51. doi:10.1016/j.shpsa.2021.06.016
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Dean G. Brown, Heike J. Wobst, Abhijeet Kapoor, Leslie A. Kenna, Noel Southall. Clinical development times for innovative drugs. Nature Reviews Drug Discovery. 2021;21(11):793-794. doi:10.1038/d41573-021-00190-9
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Rachel L. C. Barrett, Matthew Dawson, Tim B. Dyrby, et al. Differences in Frontal Network Anatomy Across Primate Species. Journal of Neuroscience. 2020;40(10):2094-2107. doi:10.1523/JNEUROSCI.1650-18.2019
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Merel Ritskes-Hoitinga, Cathalijn Leenaars, Wouter Beumer, Tineke Coenen-de Roo, Frans Stafleu, Franck L. B. Meijboom. Improving Translation by Identifying Evidence for More Human-Relevant Preclinical Strategies. Animals: an open access journal from MDPI. 2020;10(7):1170. doi:10.3390/ani10071170
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Pandora Pound. Are Animal Models Needed to Discover, Develop and Test Pharmaceutical Drugs for Humans in the 21st Century? Animals (Basel). 2020;10(12):2455. doi:10.3390/ani10122455
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