Nervous system

Manuela Cassotta, Hugo Geerts, Lise Harbom, et al. The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible. ALTEX. 2022;39(4):694-709. doi:10.14573/altex.2203161

Carolyn P. Neuhaus. Threats to Benefits: Assessing Knowledge Production in Nonhuman Models of Human Neuropsychiatric Disorders. The Hastings Center Report. 2022;52 Suppl 2(Suppl 2):S34-S40. doi:10.1002/hast.1430

Joseph J. Y. Wong, Balazs V. Varga, Ragnhildur Thóra Káradóttir, Elizabeth A. H. Hall. Electrochemically induced in vitro focal hypoxia in human neurons. Frontiers in Cell and Developmental Biology. 2022;10. doi:10.3389/fcell.2022.968341

Bilal Cakir, Yoshiaki Tanaka, Ferdi Ridvan Kiral, et al. Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids. Nature Communications. 2022;13(1):430. doi:10.1038/s41467-022-28043-y

Florencia D. Haase, Bronte Coorey, Lisa Riley, Laurence C. Cantrill, Patrick P. L. Tam, Wendy A. Gold. Pre-clinical Investigation of Rett Syndrome Using Human Stem Cell-Based Disease Models. Frontiers in Neuroscience. 2021;15. https://www.frontiersin.org/articles/10.3389/fnins.2021.698812.

Zhonglin Lyu, Jon Park, Kwang-Min Kim, et al. A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke. Nature Biomedical Engineering. 2021;5(8):847-863. doi:10.1038/s41551-021-00744-7

Foluwasomi A. Oyefeso, Alysson R. Muotri, Christopher G. Wilson, Michael J. Pecaut. Brain organoids: A promising model to assess oxidative stress-induced central nervous system damage. Developmental Neurobiology. 2021;81(5):653-670. doi:10.1002/dneu.22828

Jonas Simon Fleck, Fátima Sanchís-Calleja, Zhisong He, et al. Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases. Cell Stem Cell. 2021;28(6):1177-1180. doi:10.1016/j.stem.2021.03.015

Nienke R. Wevers, Arya Lekshmi Nair, Tania M. Fowke, et al. Modeling ischemic stroke in a triculture neurovascular unit on-a-chip. Fluids and Barriers of the CNS. 2021;18:59. doi:10.1186/s12987-021-00294-9

Katarina Stoklund Dittlau, Emily N. Krasnow, Laura Fumagalli, et al. Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition. Stem Cell Reports. 2021;16(9):2213-2227. doi:10.1016/j.stemcr.2021.03.029