Immune/infectious disease

Mart M. Lamers, Joep Beumer, Jelte van der Vaart, et al. SARS-CoV-2 productively infects human gut enterocytes. Science (New York, N.Y.). 2020;369(6499):50-54. doi:10.1126/science.abc1669

Ameen A. Salahudeen, Shannon S. Choi, Arjun Rustagi, et al. Progenitor identification and SARS-CoV-2 infection in human distal lung organoids. Nature. 2020;588(7839):670-675. doi:10.1038/s41586-020-3014-1

Jie Zhou, Cun Li, Xiaojuan Liu, et al. Infection of bat and human intestinal organoids by SARS-CoV-2. Nature Medicine. 2020;26(7):1077-1083. doi:10.1038/s41591-020-0912-6

Hiroaki Katsura, Vishwaraj Sontake, Aleksandra Tata, et al. Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction. Cell Stem Cell. 2020;27(6):890-904.e8. doi:10.1016/j.stem.2020.10.005

Janna C. Nawroth, Carolina Lucchesi, Deion Cheng, et al. A Microengineered Airway Lung Chip Models Key Features of Viral-induced Exacerbation of Asthma. American Journal of Respiratory Cell and Molecular Biology. 2020;63(5):591-600. doi:10.1165/rcmb.2020-0010MA

Arun Sharma, Gustavo Garcia, Yizhou Wang, et al. Human iPSC-Derived Cardiomyocytes Are Susceptible to SARS-CoV-2 Infection. Cell Reports. Medicine. 2020;1(4):100052. doi:10.1016/j.xcrm.2020.100052

Grégory Seumois, Ciro Ramírez-Suástegui, Benjamin J. Schmiedel, et al. Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma. Science Immunology. 2020;5(48):eaba6087. doi:10.1126/sciimmunol.aba6087

Onur Kilic, Arum Yoon, Sagar R. Shah, et al. A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm. Nature Biomedical Engineering. 2019;3:532-544. doi:10.1038/s41551-019-0366-7

Alessandro Polini, Loretta L. Del Mercato, Adriano Barra, Yu Shrike Zhang, Franco Calabi, Giuseppe Gigli. Towards the development of human immune-system-on-a-chip platforms. Drug Discovery Today. 2019;24(2):517-525. doi:10.1016/j.drudis.2018.10.003

Stucki JD, Hobi N, Galimov A, et al. Medium throughput breathing human primary cell alveolus-on-chip model. Scientific Reports. 2018;8:14359. doi:10.1038/s41598-018-32523-x